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时间:2018-10-25
《脑出血微创置管吸引术对老年脑出血患者血清il―6、tnf―α和hs―crp的影响分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、脑出血微创置管吸引术对老年脑出血患者ifc清IL—6、TNF-a和hs—CRP的影响分析[摘要]目的探讨脑出血微创置管吸引术对老年脑出血患者血清IL-6、TNF-a和hs_CRP的影响。方法选取本院2011年5月〜2013年5月收治的64例老年脑出血患者作为研究对象,随机分为对照组和观察组,各32例。对照组给予常规药物保守治疗,观察组在对照组的基础上行钻孔置管血肿抽吸液化引流术,比较两组术后2、7、15和30d的IL-6、TNF-a和hs_CRP水平。结果观察组术后7、15d的血清IL-6、TNF-a和hs_CRP水平显著低于对照组,差异有统计学意义(P0.05)。结
2、论脑出血微创置管吸引术治疗老年脑出血效果显著,能降低血清炎性因子水平,防止炎性介质损伤脑组织,值得临床推广应用。[关键词]脑出血微创置管吸引术;老年;脑出血;血清炎性因子分类号]R743.34[文献标识码]A[文章编号]1674-4721(2015)06(a)-0061-03InfluenceanalysisofcerebralhemorrhageminimallyinvasivecatheteraspirationforserumIL-6,TNF-ctandhs-CRPinelderlypatientswithcerebralhemorrhageXIAOWei-1i
3、YUANShao-pengHUJian-junDepartmentofNeurosurgery,PeoplezsHospitalofSanshuiDistrictofFoshanCityinGuangdongProvince,Foshan528100,China[Abstract]ObjectiveToexploretheinfluenceofcerebralhemorrhageminimallyinvasivecatheteraspirationforserumIL-6,TNF-ctandhs~CRPinelderlypatientswithcerebralhemo
4、rrhage.Methods64caseswithcerebralhemorrhageinourhospitalfromMay2011toMay2013wereselectedandrandomlydividedintothecontrolgroupandtheobservationgroup,32casesineachgroup.Thecontrolgroupwastreatedwithconventionalconservativetreatment,theobservationgroupwastreatedwithhematomaaspirationandliq
5、uefactionfordrillingcatheteronthebasisofthecontrolgroup.ThelevelofIL_6,TNF-aandhs~CRPinpostoperative2,7,15,30dintwogroupswascompared.ResultsThelevelofserumIL-6,TNF-aandhs~CRPinpostoperative7,15dofobservationgroupwaslowerthanthatofthecontrolgroup,withsignificantdifference(P0.05).Conclusi
6、onTheapplicationeffectofcerebralhemorrhageminimallyinvasivecatheteraspirationinthetreatmentofelderlypatientswithcerebralhemorrhageissignificant,whichcanreduceserumlevelsofinflammatorycytokines,preventdamagetobraintissue,itisworthyofclinicalpromotionandapplication.[Keywords]Cerebralhemor
7、rhageminimallyinvasivecatheteraspiration;Theelderly;Cerebralhemorrhage;Seruminflammatoryfactor老年脑出血是严重危害人类健康的脑血管疾病,具有高发病率、高致残率和高致死率等特点[1]。临床治疗老年脑出血的难度较大,单纯内科保守治疗周期长,疗效不尽满意,患者死亡率高[2]。高血压性脑出血是临床神经外科的常见病、多发病,其中基底节出血最常见,约占60%,大多是由于各种因素引起血压骤升,导致颅内动脉破裂形成血肿,产生占位效应,并且随着时间的推进,脑组织水肿将进一步加
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