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ID:13899851
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时间:2018-07-24
《q开关nd-yag激光联合重组人表皮生长因子治疗颧部褐青色痣疗效观察》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、Q开关Nd:YAG激光联合重组人表皮生长因子治疗颧部褐青色痣疗效观察[摘要]目的:评价Q开关Nd:YAG激光联合重组人表皮生长因子(recombinanthumanepidermalgrowthfactor,rhEGF)在治疗颧部褐青色痣(naevusfuscocaeruleuszygomaticusNFZ)过程中对减轻色素沉着,缩短疗程的作用。方法:对2004年12月~2007年12月采用Q开关Nd:YAG激光治愈的52例颧部褐青色痣患者的临床资料进行回顾性分析,治疗组27例(治疗后外涂重组人表皮生长因子),
2、对照组25例(治疗后待自然愈合),比较其治疗间隔时间、疗程的长短。结果:治疗组与对照组平均治疗间隔时间分别为74.59天及105.24天,平均疗程分别为453.37天及651.28天,两组差异有统计学意义(P<0.05)。结论:Q开关Nd:YAG激光联合重组人表皮生长因子治疗颧部褐青色痣色素沉着轻、疗程较短,值得临床推广。[关键词]Q开关Nd:YAG激光;颧部褐青色痣;重组人表皮生长因子;疗效[中图分类号]R758.51[文献标识码]A[文章编号]1008-6455(2008)06-0892-03Theobse
3、rvationoftheraperticeffectofnaevusfuscocaeruleuszygomaticustreatedbyQ-switched9Nd:YAGlaserassociatedwithrecombinanthumanepidermalgrowthfactorYANGHai-bo,LIDa-tie,ANLi-sha,WENYang,TANGZheng-xi(DepartmentofCosmeticLaser,theCosmeticHospitaloftheAffiliatedHospita
4、lofZunyiMedicalCollege,Zunyi563003,Guizhou,China)Abstract:ObjectiveToevaluatethetherapeuticeffectofnaevusfuscocaeruleuszygomaticustreatedbyusingQ-switchedNd:YAGlaserassociatedwithrecombinanthumanepidermalgrowthfactortolessenpigmentationanddecurtatecourseoftr
5、eatment.MethodsToreviewandanalysizetheclinicaldataof52patientswithNFZwhichhavebeenrecoveredinthepastyearsrangedfrom2004.12to2007.12.Allthecasesweredividedintotwogroups:thetherapicgroupwith27caseswereappliedrhEGFafterthetreatmentandthecontrolgroupwith25casesw
6、erehealedradomlytocompareintervaltimeandcourseoftreatment.ResultsTheaverageintervaltimeofthetherapicgroupandthecontrolgroupwasrespectively74.59daysand105.24days,9andtheaveragetimeoftherapyofbothgroupswasrespectively453.37daysand651.28days.Thedifferenceofthem
7、wasstatisticalsignificance(P<0.05).ConclusionThetherapicmethodofNFZbyQ-switchedNd:YAGlaserassociatedwithrhEGF.isworthgeneralizationinclinicbecauseoflesspigmentationandshortertimeoftherapyKeywords:Q-switchedNd:YAGlaser;naevusfuscocaeruleuszygomaticus;recombin
8、anthumanepidermalgrowthfactor;therapeuticeffect颧部褐青色痣(naevusfuscocaeruleuszygomaticus,NFZ)是对称分布于双侧颧部、颞部、上眼睑外侧,呈青褐色、棕褐色及黄褐色群集而不融合的圆形或卵圆形的色素性皮肤病。传统的治疗方法,如冷冻、磨削、化学剥脱术等疗效不佳。目前认为应用Q开关Nd:YAG激光治疗NFZ是一种
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