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时间:2020-05-19
《皮肤镜诊断头面部色素型基底细胞癌的临床研究.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中华临床医师杂志f电子版12014年2月第8卷第3期ChinJClinicians(ElectronicEdition)。Februar~l,2014’v01墨『0.·临床论著·皮肤镜诊断头面部色素型基底细胞癌的临床研究李琨边培雯张雪洁马静霖高敏虹司晓青孙晓慧辛琳琳【摘要】目的探讨皮肤镜在诊断头面部色素型基底细胞癌中的价值。方法选择48例临床拟诊为色素型基底细胞癌患者,发病部位位于头面部,年龄37~86岁,男24例,女24例,对其行皮肤镜检查。由两名医师参照色素型基底细胞癌皮肤镜特点,盲法独立诊断,再以病理诊断为金标准,通过诊断性试验的研究方法,研究皮肤镜在诊断头
2、面部色素型基底细胞癌的灵敏度和特异度及与病理诊断的一致性。结果48例患者中36例经组织病理学诊断为色素型基底细胞癌,医师A皮肤镜诊断为色素型基底细胞癌的34例,非色素型基底细胞癌14例:医师B皮肤镜诊断为色素型基底细胞癌的38例,非色素型基底细胞癌10例。与组织病理诊断比较,两名医师皮肤镜诊断头面部色素型基底细胞癌的正确率、灵敏度、特异度、误诊率、漏诊率、Youden指数、Kappa值分别是91.67%、91.67%、91.67%、8.33%、8.33%、83.34%、0.7895和91.67%、97_22%、75%、25%、2.78%、66.22%、0.7648
3、,两名医师经皮肤镜诊断头面部色素型基底细胞癌的水平经卡方检验无统计学差异(=0.889,P>O.050)。结论头面部色素型基底细胞癌皮肤镜诊断结果与组织病理学结果有较好的一致性,具有重要的诊断价值。【关键词】皮肤镜检查;癌,基底细胞:诊断TheclinicalresearchofdermoscopyinthediagnosisofheadfacialpigmentedbasalcellcarcinomaLiKun,BianPeiwen,Zhangejie,MaJinglm,GaoMinhong,SiXiaoqing,SunXiaohu~X{nLinlin.Shan
4、dongAcademyofMedicalSciences,Jinan250062,ChinaCorrespondingauthor:XinLinlin,Email:Xinll158@sina.corn[Abstract]ObjectiveToexplorethevalueofdermoscopyinthediagnosisofheadfacialpigmentedbasalcellcarcinoma.Methods48patientsn1headfaciallesionswhosuspectedforpigmentedbasalcellcarcinomaweree
5、nrolledinthisstudy.Therewere24malesand24femalesamongpatientsaged37to86yearsold.Thesuspectedlesionswereexaminedbydermoscopy,then,twodoctorsindependentlymadeadiagnosisaccordingtothephotosfromthedermoscopy.Thesensitivity,specificityandconsistencywithhistopathologywerecalculatedfordermosc
6、opyinthediagnosisofheadfacialpigmentedbasalcellcarcinoma.ResultsOfthe48patients,36werediagnosedpigmentedbasalcellcarcinomaaccordingtopathologicalfindings.Basedonthedermoscopicfeatures,34caseswerediagnosedaspigmentedbasalcellcarcinomabydoctorA,and38bythedoctorB.Theaccuracy,sensitivity,
7、specificity,misdiagnosisrate,rateofmisseddiagnosis,YoudenindexandKappavalueofdermoscopywere91.67%,91.67%,91.67%,8.33%,8.33%,83.34%,0.7895respectivelyinthediagnosisofheadfacialpigmentedbasaleellcarcinomabythedoctorA.91.67%,97_22%,75%,25%,2.78%,66.22%,0.7648respectivelybythedoctorB.Thet
8、wodoc
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