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《腹腔镜和开腹胃癌根治术在进展期胃癌中临床疗效和对细胞免疫功能影响.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、腹腔镜和开腹胃癌根治术在进展期胃癌中un临床疗效和对细胞免疫功能影响［摘要］目的比较腹腔镜根治术与传统开腹术在进展期胃癌中的临床疗效及对细胞免疫功能的影响。方法选择2010〜2012年丽水市人民医院收治胃癌患者106例，随机分为观察组和对照组，每组各53例，观察组接受腹腔镜根治术，对照组接受传统开腹术治疗，比较两组患者的近期疗效及细胞免疫功能。结果①观察组患者切口长度、手术时间、术中出血量、术后排气时间、术后住院时间分别为(7.28±1.23)cm、(168.12±28.36)min.(131.24±26.57)
2、mL、(3.24±1.26)d和(11.39±2.84)d,与对照组比较，差异均有统计学意义(t二11.477、6.163、7.456、5.685、4.534,P0.05)o②术后观察组患者CD4+、CD4+/CD8+分别为(27.21±3.98)%和(0.89±0.16),与对照组比较，差异有统计学意义(t=6.153、4.979,P0.05)。结论腹腔镜根治术治疗胃癌的近期临床效果优于传统开腹术，并且对患者的细胞免疫功能抑制作用较轻，值得临床推荐。［关键词］胃癌；腹腔镜；传统开腹术；临床疗效；细胞免疫功能［中
3、图分类号］R735.2［文献标识码］A［文章编号］1673-7210(2014)01(c)-0064-04Comparisononshort-termclinicalefficacyandcellularimmunefunctionoflaparoscopy-assistedradicalgastrectomyandtraditionallaparotmyinthetreatmentofgastriccancerMOULilQIANRong21.DepartmentofGeneralSurgery,thePeop
4、le"sHospitalofLishuiCity，ZhejiangProvince,Lishui323000,China；2.DepartmentofGeneralSurgery,thePeople'sHospitalofZhejiangProvince,ZhejiangProvince,Hangzhou310014,China[Abstract]ObjectiveTocomparetheshort-termclinicalefficacyandcellularimmunefunctionoflaparoscop
5、y-assistedradicalgastrectomyandtraditionallaparotmyinthetreatmentofgastriecancer.MethodsAtotalof106patientswithgastriecancerinthePeople"sHospitalofLishuiCityfrom2010to2012wereselectedanddividedintoobservetiongroupandcontrolgroupwith53casesineachgroup・Patients
6、inobservationgroupweretreatedwithlaparoscopy-assistedradicalgastrectomyandthecontrolgroupwastreatedwithtraditionalopensurgery.Theshort~termclinicalefficacyandcellularimmunefunctionwerecomparedinthetwogroups・Results①Lengthofcut，durationofoperation，amountofbloo
7、dlossduringoperation,evacuationtimeafteroperation，andhospitalstaysafteroperationinobservationgroupwere(7.28±1.23)cm,(16&12+28.36)min,(131.24土26.57)mL,(3.24+1.26)dand(11.39+2.84)drespectively,thedifferenceswerestatisticallysignificantwithcontrolgroup(t二11.477，
8、6.163,7.456，5.685,4.534,P0.05).②CD4+andCD4+/CD8+afteroperationinobservationgroupwere(27.21+3.98)%and(0.89+0.16)respectively，thedifferenceswerestatisticallysignificantwithcontrolgroup(t=6.
