高分辨力MRI测量中国汉族正常成人豆状核.pdf

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1、中国医学影像技术2012年第28卷第1期ChinJMedImagingTeehnol，2012，Vol28，No1·15·◆◆．軎’(论MeasuringthevolumeofthelentiformnucleusinhealthyChineseadultsbasedonhigh。resolutionMRIW_ANGGuo—kun，CHENNan，W_ANGXing，ZHUOYan。，CHENLin。，LIKun—cheng“，W_ANGDan“．SHENBao—zhong(1．DepartmentofRadiology，theFourthHospitalofHarbi

2、nMedicalUniversity，Harbin150001，China；2．DepartmentofRadiology，XuanwuHospital，CapitalMedicalUniversity，Beijing100053，China；3．StateKeyLaboratoryofBrainandCognitiveScience，InstituteofBiophysics，ChineseAcademyofSciences，Beijing100101，China)[Abstract]ObjectiveTomeasurethevolumeofthelentiformn

3、ucleusinChineseadultsofHannationality，inordertoprovidedatabaseforresearchingonavarietyofdiseasesassociatedwith1entiformnucleus．MethodsTotally1000volun—teers(agedfrom18to70)wererecruitedinthismulti—centerstudyanddividedinto5groupsaccordingtotheage(18—3O，31—4O，41～5O，51—6O，61—8O)．Eachgroupi

4、ncluded1O0menand1O0women．AIlthevolunteersunderwentMRex—aminationusingT1weightedthree—dimensionalmagnetizationpreparedrapidacquisitiongradientechosequence．Thevol—umeoflentiformnucleuswasmeasuredmanuallyusing3Dvolumeanalysissoftware．Therelationshipbetweenthevolumeoflentiformnucleusandage，a

5、swellassexwasanalyzed．ResultsThemeanvolumeofleftandrightputamenin1000vol—unteerswere(4811．59±588．99)mm。and(4763．11±587．59)mm。，andthevolumeofleftputamenwas1argerthanthatofrightputamen(f一10．134，P<0．0001)．Themeanvolumeofleftandrightglobuspalliduswere(1591．31±226．81)mm。and(1627．28士235．06)mm。

6、，andthevolumeofrightglobuspalliduswaslarger(￡一一9．877．P<0．0001)．Themeanvolumeofleftandrightputamenandglobuspalliduswere(4962．72士598．49)mm。，(4909．83±600．54)ram。，(1623．24~234．16)mm。and(1663．18±243．56)mm。，respectivelyformen，whileforwomenwere(4663．65士540．49)mm。，(4619．28±537．59)mm。，(1560．O0±21

7、5．04)mm。and(1592．09士221．06)mm。，respectively．Menhadlargerputamenandglobuspallidusthanwomen(allP<0．0001)．Thevolumeoftheleftandrightputamen，aswellastheleftandrightglobuspalliduswereallnegativelycorrelatedwithage．ConclusionThevolumeoftheleftputamenislargerthanthatoftheright．a