中国正常成人中脑体积的高分辨力MRI的测量与分析.pdf

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1、中国医学影像技术2012年第28卷第1期ChinJMedImagingTechnol,2012,Vol28,No1·23·——◆．◆．专’(论MeasuringandanalyzingthevolumeofmidbraininhealthyChineseadultssUNL。CHENNan。，WANGXing，WANGDan，ZHUOYah。，CHENLin。．LJKun—cheng“，SHENBao—zhong”(1．DPPⅡrtmentofRadiology，f^PFourthHospitalofHarbinMedicalUniversit

2、y，Harbin150001，China2．DepartmentofRadiology，XuanwuHospital，CapitalMedicalUniversity，Beijing100053，China；3．StateKeyLaboratoryofBrainandCognitiveScience，InstituteofBiophysics，ChineseAcademyofSciences，Beijing100101，China)[Abstract]ObjectiveTomeasurethevolumeofmidbraininhealthyC

3、hineseadultsofHannationality，andtoexploretherelationshiDbetweenmidbrainvolumesandageandsex，inordertoprovidemorphologicaldatafortheconstructionofda—tabaseofstandarddigita1brainofChinesepeople．MethodsTotally1000healthyvolunteerswererecruitedanddividedinto5groups(groupA—E)accor

4、dingtoage：18—3O，31—4O，41—5O，51—6O，61—7Oyear-old．Eachgroupincluded200volunteerswith100ma1eand100female．AllthesubjectsunderwentthreedimensionalMRscan，andwholebrainvolumewasobtainedwith3Dvolumeanalysissoftware．Correlationofagewithmidbrainvolumeswereanalyzedstatistically．ResuIts

5、Themidbrainvolumeofmaleandfemalewas(8087．89士1177．43)mm。and(7763．87士1007．44)mm。，respec—tive1v(一一4．68，P<0．001)．Themidbrainvolumesinthefivegroupswere(8857．65土980．12)mm。，(8691．22±913．56)mm3。(8072．26±1024．78)mm3，(7688．33士981．91)mm3，(7129．98士1059．98)mm。inmaleand(8290．68士995．41)mm3

6、．(8034．79±1000．oo)mm。，(7767．43士907．28)mm。，(7619．18土836．72)mm。and(7107．29±889．09)mm。infemale．MidbrainvolumesingroupA—Cinmalewerelargerthanthoseinfemale(allP<0．05)，whiletherewasnodifferencebetweenmaleandfemaleinthegroupDandE．Eachgroupwasdifferentfromotherssignificantly(allP<0．

7、05)，besidesgroupAandBinmaleandgroupAandB，groupCandDinfemale．Midbrainvolumesinfemaleandmalewerea11correlatedwithages(r一一0．55，一0．38，bothP

8、ld，whilenodifferencesisfoundbetweenthetwosexesin51—7Oyearsold．Themidbrainvo