[经典]波前像差引导的个体化切削矫正常规LASIK偏中心切削临床观察.doc

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1、［经典］波前像差引导的个体化切削矫正常规LASIK偏中心切削临床观察波前像差引导的个体化切削矫正常规LASIK偏中心切削临床观察【摘要】目的评价波前像差引导的个体化切削矫正常规准分子激光角膜原位磨镶术(LASIK)光学区偏中心切削的有效性、安全性和可预测性。方法13例16眼光学区偏中心切削的LASIK患者，经OPDSCAN检查眼部像差后导入Final-fit软件进行设计，应用偏中心模式进行手术。结果术后随访时间(7.31±2.98)m(3^15m),无特殊并发症发生。术后3ni裸眼视力由0.58±0.23提高到0.99±0.11,总

2、像差、高阶像差、彗差分别由术前(3.620±2.122)(0.954±0.240)5、(0.823±0.361)5降至(1.551±0.871)(0.454±0.109)he、(0.334±0.127)nm,差异有显著统计学意义(P<0.01)o角膜地形图显示偏中心明显矫正［术前(0.91±0.33)mm,术后(0.43±0.21)mm,P<0.01］,患者视觉质量明显提高。结论波前像差引导的个体化切削矫正常规LASIK后光学区偏中心切削效果理想，预测性好，安全性高，是矫治偏中心切削的理想处理方法。【关键词】波前像差;偏中心切削Wa

3、vefrontaberrationguidingcustomizedablationstocorrectdecenteredablationofconventionalLASIKZHULiang-yong,HEZhi-li,CHENFeng-1ian,etal.Departmentofophthalmology,theFourthAffiliatedhospitalofGuangxiMedicalUniversity,LiuzhouGuangXiprovince545005,China[Abstract]ObjectiveToeva

4、luatetheefficacy,safetyandpredictabilityofwavefrontaberrationguidingcustomizedablationsfordecenteredablationsfollowinglaserinsitukeratomileusis(LASIK).Methodsl3patients(16eyes)withdecenteredablationsunderwenttraditionalLASIK.Wavefront-supportedcustomizedablation(WASCA)

5、wasperformedusingOPD-SCANtoobtainacustomizedablationprofileandFinalFitsoftwaretodesign.ResultsMeanfollow-upwas(7.31±2.98)months(range,3^15months).Nointra-orpostoperativecomplicationswereobserved.Meanuncorrectedvisualacuityimprovedsignificantly(P<0.01)from(0.58±0.23)(ra

6、nge,0.2~1.0)to(0.99+0.11)(range,0.8~1.2)at3monthspost-WASCA.Totalwavefrontaberration^higher-orderaberrations^comawasastatisticallysignificantreductionfrom(3.620±2.122)nm,(0.954±0.240)nmand(0.823±0.361)umatpre-WASCAto(1.551+0.871)Pm,(0.454±0.109)umand(0.334+0.127)umresp

7、ectivelyat3monthspost~WAGCA(P<0.01).Eccentricityshowedastatisticallysignificantreductionaftertreatment[pre-WASCA:(0.91±0.33)mm;post-WASCA:(0.43±0.21)mm;P<0.01]andpatientsVisualqualityimprovedsignificantly.ConelusionWavefrontaberrationguidingcustomizedablationsfordecent

8、eredablationsfollowingLASIKwassafe,effectiveandpredictable.[Keywords]Wavefrontaberration;Decenteredablation准分子激光角膜原位位