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时间:2020-05-24
《蟾毒灵对人肝癌细胞增殖与侵袭的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、1Ir辱年^渣化泰立’⑩世界华人消化杂志2014年5月18~q;22(14):1921—1927wcjd@wjgnet.cornISSN1009—3079(print)ISSN2219—2859(online)基础研究BASICRESEARCH蟾毒灵对人肝癌细胞增殖与侵袭的影响盖吉钦,秦建民,范跃祖盖吉钦,同济大学医学院上海市2t)0065mentwithbufalinatadoseof0.085pg/mLfor●背蒜资料盖吉钦,秦建民,上海中医药大学附属普陀医院普外科上海原发性肝癌是较72hsignificantlyinhibitedthemigration(t市2
2、00()62常见的消化系肿范跃祖,同济大学附属同济医院普外科上海市2()(1(/6511.717,P3、inqin@yahoocomandinvasionofhumanlivercancercells.Be—蟾毒灵(bufa1jn,电话:021—22233219sides,bufalincaninhibittheproliferationofhu—Bu)是传统抗肿瘤收稿日期:2014—03—03修回日期:2014—03-13manlivercancerceilsbyblockinKthecellcycle中药蟾酥中主要接受日期:2014—03—18在线出版日期:2014-05—18的活性成分之一.inG,/Sphase.Theanti.proliferativeeffe4、ctof具有明确的抗肿bufalinisdose—andtime—dependent.瘤效果.为了进一Bufalininhibitsproliferation步明确Bu抗肝癌⑥2014BaishidengPublishingGroupCo.,Limited.AI的机制,本研究对andinvasionofhumanliverBi.i对肝癌细胞增rightsreserved.cancercells殖侵袭作用的影响进行了观察.KeyWords:Bufalin;Livercancercells;Proliferation;Ji-QinGai,Jian‘MinQin,Yue-Z5、uFanInvasion;EffectJi-QinGai,MedicalSchoolofTongjiUniversity,ShanghaiGaiJQ,QinJM,FanYZ.Bufalininhibitsproliferation200065,Chinaandinvasionofhumanlivercancercells.ShijieHuarenJi-QinGai,Jian-MinQin,DepartmentofGeneralSurgery,XiaohuaZazhi2014;22(14):1921—1927URL:http://PutuoHospita1.Shangh6、aiUniversityofTraditionalChinese,WWW.wjgnetcom/1009—3079/22/1921.aspDOI:http://Shanghai200062,Chinadx.doi.org/10.11569/wcjd.v22.i14.1921Yue·ZuFan,DepartmentofGeneralSurgery,Ton自iHos—pital,ShanghaiTbniUniversity,Shanghai200065,ChinaCorresDOndenceto:Jian.Minqin,ChiefPhysician、De—partmento7、fGeneralSurgery。PutuoHospital,Shanghai摘要UniversityofTraditionalChinese.164LanxiRoad.PutuoDistrict,Shanghai200062,China.iianminqin@yahoo.com目的:研究蟾毒灵(bufalin,Bu)对肝癌BEL一7402Received:2O14—03—03Revised:20l4—03-13细胞生长、迁移侵袭的作用.Accepted:2014—03—18Publishedonline:2Ol4—05一l8方法:体外培养人肝癌BEL
3、inqin@yahoocomandinvasionofhumanlivercancercells.Be—蟾毒灵(bufa1jn,电话:021—22233219sides,bufalincaninhibittheproliferationofhu—Bu)是传统抗肿瘤收稿日期:2014—03—03修回日期:2014—03-13manlivercancerceilsbyblockinKthecellcycle中药蟾酥中主要接受日期:2014—03—18在线出版日期:2014-05—18的活性成分之一.inG,/Sphase.Theanti.proliferativeeffe
4、ctof具有明确的抗肿bufalinisdose—andtime—dependent.瘤效果.为了进一Bufalininhibitsproliferation步明确Bu抗肝癌⑥2014BaishidengPublishingGroupCo.,Limited.AI的机制,本研究对andinvasionofhumanliverBi.i对肝癌细胞增rightsreserved.cancercells殖侵袭作用的影响进行了观察.KeyWords:Bufalin;Livercancercells;Proliferation;Ji-QinGai,Jian‘MinQin,Yue-Z
5、uFanInvasion;EffectJi-QinGai,MedicalSchoolofTongjiUniversity,ShanghaiGaiJQ,QinJM,FanYZ.Bufalininhibitsproliferation200065,Chinaandinvasionofhumanlivercancercells.ShijieHuarenJi-QinGai,Jian-MinQin,DepartmentofGeneralSurgery,XiaohuaZazhi2014;22(14):1921—1927URL:http://PutuoHospita1.Shangh
6、aiUniversityofTraditionalChinese,WWW.wjgnetcom/1009—3079/22/1921.aspDOI:http://Shanghai200062,Chinadx.doi.org/10.11569/wcjd.v22.i14.1921Yue·ZuFan,DepartmentofGeneralSurgery,Ton自iHos—pital,ShanghaiTbniUniversity,Shanghai200065,ChinaCorresDOndenceto:Jian.Minqin,ChiefPhysician、De—partmento
7、fGeneralSurgery。PutuoHospital,Shanghai摘要UniversityofTraditionalChinese.164LanxiRoad.PutuoDistrict,Shanghai200062,China.iianminqin@yahoo.com目的:研究蟾毒灵(bufalin,Bu)对肝癌BEL一7402Received:2O14—03—03Revised:20l4—03-13细胞生长、迁移侵袭的作用.Accepted:2014—03—18Publishedonline:2Ol4—05一l8方法:体外培养人肝癌BEL
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