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时间:2020-05-23
《罗库溴铵和顺式阿曲库铵用于肝部分切除术肌松效应的比较.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·430·临床麻醉学杂志2014年5月第3O卷第5期JCiinAnesthesiol,May2014,V。L30,No.5.临床研究.罗库溴铵和顺式阿曲库铵用于肝部分切除术肌松效应的比较邓城旗李萌萌郝建华【摘要】目的比较罗库溴铵和顺式阿曲库铵用于肝部分切除术的肌松效应。方法择期全麻下行剖腹单纯肝部分切除术患者40例,随机均分为罗库溴铵组(R组)和顺式阿曲库铵组(C组)。全麻肌松药诱导量R组和C组分别为2倍EI)9的罗库溴铵0.6mg/kg及顺式阿曲库铵0.1mg/kg,采用TOF监测肌松程度,当TOFr至25时追加肌松
2、药。观察两组肌松药起效时间、气管插管条件、临床作用时间、术毕恢复指数、气管拔管时间及不良反应。结果R组起效时间明显快于、临床作用时间及术毕恢复指数明显长于C组(P<0.05);两组气管拔管时间差异无统计学意义。当TO—Fr为0时,R组气管插管条件为优的例数明显多于C组(P3、时间长,虽恢复指数略长,但对拔管时间并无影响,同时未有明显的肌松残余作用,可以安全用于肝部分切除术的患者。【关键词】肌松药;罗库溴铵;顺式阿曲库铵;肝部分切除术;术后肌松残余作用ComparisonofneuromuscularblockadeeffectofrocuroniumwitheisatracuriuminpatientsundergoingpartialhepatectomyDENGCheng-qi.LJMeng-meng,HAOJian—hua.DepartmentofAnesthesiolo—gY,Fi4、rstAffiliatedHospitalofGeneralHospitalof,Beifing100048,ChinaCorrespondingauthor:L,Meng-meng,Email:lemontea7661@gmail.com[Abstract]ObjectiveToobservecomparisonofneuromuscularblockadeeffectofrocuroniumwithcisatracuriuminpatientsundergoingpartialhepatectomy.Methods5、FortyASAstatusI一Ⅲpa—tientsscheduledforpartialhepatectomywereenrolledinthestudy.Patientswererandomlyassignedtotwotreatmentgroups(一2O).GroupRreceivedroeuronium0.6mg/kgandgroupCreceivedci—satracurium0.1mg/kgasinductiondose.Neuromuscularblockadewasevaluatedwithtrain6、-of-four(T0F)stimulioftheulnarnerve.Additionaldose(0.1mg/kgor0.03mg/kg)wereadministeredtokeeptheTOFrate(TOFr)at0tO0.25.Thetimeofdepression,durationofaction,andrecoveryin—dextimewererecorded.ResultsTimeofonsetwassignificantlyshorterinpatientsreceivingrocuro—niumt7、hancisatracurium(P8、ngroupRwassignificantlyinhigherthangroupC(P
3、时间长,虽恢复指数略长,但对拔管时间并无影响,同时未有明显的肌松残余作用,可以安全用于肝部分切除术的患者。【关键词】肌松药;罗库溴铵;顺式阿曲库铵;肝部分切除术;术后肌松残余作用ComparisonofneuromuscularblockadeeffectofrocuroniumwitheisatracuriuminpatientsundergoingpartialhepatectomyDENGCheng-qi.LJMeng-meng,HAOJian—hua.DepartmentofAnesthesiolo—gY,Fi
4、rstAffiliatedHospitalofGeneralHospitalof,Beifing100048,ChinaCorrespondingauthor:L,Meng-meng,Email:lemontea7661@gmail.com[Abstract]ObjectiveToobservecomparisonofneuromuscularblockadeeffectofrocuroniumwithcisatracuriuminpatientsundergoingpartialhepatectomy.Methods
5、FortyASAstatusI一Ⅲpa—tientsscheduledforpartialhepatectomywereenrolledinthestudy.Patientswererandomlyassignedtotwotreatmentgroups(一2O).GroupRreceivedroeuronium0.6mg/kgandgroupCreceivedci—satracurium0.1mg/kgasinductiondose.Neuromuscularblockadewasevaluatedwithtrain
6、-of-four(T0F)stimulioftheulnarnerve.Additionaldose(0.1mg/kgor0.03mg/kg)wereadministeredtokeeptheTOFrate(TOFr)at0tO0.25.Thetimeofdepression,durationofaction,andrecoveryin—dextimewererecorded.ResultsTimeofonsetwassignificantlyshorterinpatientsreceivingrocuro—niumt
7、hancisatracurium(P8、ngroupRwassignificantlyinhigherthangroupC(P
8、ngroupRwassignificantlyinhigherthangroupC(P
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