欢迎来到天天文库
浏览记录
ID:53730723
大小:289.27 KB
页数:4页
时间:2020-04-20
《体温对老年人顺式阿曲库铵与罗库溴铵恢复时相影响的比较.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、ShanghaiMedJ,2012,Vo1.35,No.6·484·●临床麻醉●体温对老年人顺式阿曲库铵与罗库溴铵恢复时相影响的比较吴敏仙李士通【摘要】目的比较不同体温对老年患者术后顺式阿曲库铵和罗库溴铵肌肉松弛恢复的影响。方法择期在全身麻醉下行手术的老年患者8O例,随机分为顺式阿曲库铵不保温、顺式阿曲库铵保温、罗库溴铵不保温及罗库溴铵保温组,每组2O例。采用全身麻醉联合硬脊膜外腔阻滞麻醉,全身麻醉诱导气管插管时给予顺式阿曲库铵0.15mg/kg或罗库溴铵0.6mg/kg,术中肌肉松弛药经静脉输液泵输注维持,持续监测肌肉松弛和鼻咽温度
2、,记录患者的药物累积剂量,手术时间,静脉注射肌肉松弛药到第1个肌颤搐高度(T)最大抑制的时间(起效时间),T从25恢复到75的时间(肌肉松弛恢复指数),T恢复至25到4个成串刺激(TOF)比值(TOFR,即TOF中第4个肌颤搐高度与T的比值)恢复至9O的时间(完全恢复时间),以及麻醉诱导时、T恢复至25时、TOFR恢复至9O时的温度。结果术毕两个不保温组的体温显著低于两个保温组(P值均3、库溴铵不保温、罗库溴铵保温组(P值均0.05),而肌肉松弛恢复指数和完全恢复时间均显著短于两个不保温组(P值均4、acuriumandrocuroniuminelderlypatientsWUMinxian,LIShitong.DepartmentofAnesthesiology,ShanghaiFirstPeople’sHospital,ShanghaidiaotongUniversity,Shanghai200080,ChinaCorrespondingauthor:LIShitong【Abstract]ObjectiveToinvestigatetheefectofbodytemperatureonthepostoperativerelax5、ationrecoveryofcisatracuriumandrocuroniuminelderlypatients.MethodsEightyelderlypatientsscheduledforelectivesurgerywererandomlydividedintothefollowing4groups:non-heatpreservingcisatracuriumgroup,heatpreservingcisatracuriumgroup,non—heatpreservingrocuroniumgroup,andheatpr6、eservingrocuroniumgroup(n=20).Allpatientsreceivedgeneralanaesthesiacombinedwithepiduralanaesthesia.Intubationwasconductedwithcisatracurium015mg/kgorrocuronium06mg/kgaccordingtothegrouping.MusclerelaxantswereinfusedbyvenouspumpduringoperationThetemperatureandmusclerelaxa7、tionparameterswererecordedduringthewholeprocedure,includingtheonsettimeandaccumulateddoseoftherelaxant;operationtime,durationsofT1recoverytO25%,50%and75%;durationsofTOFRrecoveryto90%;nasOpharyngealtemperaturesatinduction;25%T1recoveryand90%TOFRrecovery.ResultsPatientsin8、thenon—heatpreservinggroupshadalowerbody.temperaturecomparedwiththeheatpreservinggroupsaftersurgery(P<0.01).Th
3、库溴铵不保温、罗库溴铵保温组(P值均0.05),而肌肉松弛恢复指数和完全恢复时间均显著短于两个不保温组(P值均4、acuriumandrocuroniuminelderlypatientsWUMinxian,LIShitong.DepartmentofAnesthesiology,ShanghaiFirstPeople’sHospital,ShanghaidiaotongUniversity,Shanghai200080,ChinaCorrespondingauthor:LIShitong【Abstract]ObjectiveToinvestigatetheefectofbodytemperatureonthepostoperativerelax5、ationrecoveryofcisatracuriumandrocuroniuminelderlypatients.MethodsEightyelderlypatientsscheduledforelectivesurgerywererandomlydividedintothefollowing4groups:non-heatpreservingcisatracuriumgroup,heatpreservingcisatracuriumgroup,non—heatpreservingrocuroniumgroup,andheatpr6、eservingrocuroniumgroup(n=20).Allpatientsreceivedgeneralanaesthesiacombinedwithepiduralanaesthesia.Intubationwasconductedwithcisatracurium015mg/kgorrocuronium06mg/kgaccordingtothegrouping.MusclerelaxantswereinfusedbyvenouspumpduringoperationThetemperatureandmusclerelaxa7、tionparameterswererecordedduringthewholeprocedure,includingtheonsettimeandaccumulateddoseoftherelaxant;operationtime,durationsofT1recoverytO25%,50%and75%;durationsofTOFRrecoveryto90%;nasOpharyngealtemperaturesatinduction;25%T1recoveryand90%TOFRrecovery.ResultsPatientsin8、thenon—heatpreservinggroupshadalowerbody.temperaturecomparedwiththeheatpreservinggroupsaftersurgery(P<0.01).Th
4、acuriumandrocuroniuminelderlypatientsWUMinxian,LIShitong.DepartmentofAnesthesiology,ShanghaiFirstPeople’sHospital,ShanghaidiaotongUniversity,Shanghai200080,ChinaCorrespondingauthor:LIShitong【Abstract]ObjectiveToinvestigatetheefectofbodytemperatureonthepostoperativerelax
5、ationrecoveryofcisatracuriumandrocuroniuminelderlypatients.MethodsEightyelderlypatientsscheduledforelectivesurgerywererandomlydividedintothefollowing4groups:non-heatpreservingcisatracuriumgroup,heatpreservingcisatracuriumgroup,non—heatpreservingrocuroniumgroup,andheatpr
6、eservingrocuroniumgroup(n=20).Allpatientsreceivedgeneralanaesthesiacombinedwithepiduralanaesthesia.Intubationwasconductedwithcisatracurium015mg/kgorrocuronium06mg/kgaccordingtothegrouping.MusclerelaxantswereinfusedbyvenouspumpduringoperationThetemperatureandmusclerelaxa
7、tionparameterswererecordedduringthewholeprocedure,includingtheonsettimeandaccumulateddoseoftherelaxant;operationtime,durationsofT1recoverytO25%,50%and75%;durationsofTOFRrecoveryto90%;nasOpharyngealtemperaturesatinduction;25%T1recoveryand90%TOFRrecovery.ResultsPatientsin
8、thenon—heatpreservinggroupshadalowerbody.temperaturecomparedwiththeheatpreservinggroupsaftersurgery(P<0.01).Th
此文档下载收益归作者所有