资源描述:
《顺式阿曲库铵与罗库溴铵用于全麻气管插管的临床效果分析》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、顺式阿曲库钱与罗库漠铃用于全麻气管插管的临床效果分析[摘要]日的探讨顺式阿曲库钱和罗库漠鞍分别用于全麻诱导气管插管的效果。方法将124例行全麻气管插管腹部手术的患者随机分为顺式阿曲库钱组和罗库澳鞍组,各62例,经静脉注入咪达啤仑0.1mg/kg,芬太尼3ug/kg进行麻醉诱导,待患者意识和睫毛反射消失后,顺式阿曲库鞍组给予顺式阿曲库较0.15mg/kg,罗库混较组给予罗库滉鞍0.6mg/kg后行气管插管,比较气管插管的总有效率及两组患者诱导前、插管后1、5min时平均动脉压(MAP)、脉搏氧饱和度(Sp02)、心率(HR)的变化,记录全麻
2、诱导的起效时间、作用时间、恢复指数及组胺释放情况。结果罗库澳钱组气管插管总有效率为95.2%,打顺式阿曲库钱组(88.6%)比较差异冇统计学意义(x2=l・74,P<0.05);两组患者插管后1min的MAP、HR明显上升(P〈0・05),5min后与诱导前无明显差异;罗库漠鞍组的起效时间和作用时间较短,恢复指数也明显低于顺式阿曲库鞍组,差异有统计学意义(P<0.05)。结论罗库澳钱用于全麻气管插管术的起效时间短,恢复迅速,是临床上较理想的肌松药。[关键词]气管插管;顺式阿曲库鞍;罗库漠鞍;起效时间[中图分类号]R614.2[文献标识码]
3、A[文章编号]1673-7210(2014)04(a)-0058-03ClinicaleffectanalysisofCisatracuriumandRocuroniumfortrachealintubationgeneralanesthesiaTONGBotaoSUNHaoXUXinDUANJiafangDepartmentofAnesthesiology,NO.81HospitalofChinesePeople'sLiberationArmy,JiangsuProvince,Nanjing210002,China[Abstract]O
4、bjectiveToinvestigatetheeffectofCisatracuriumandRocuroniumfortrachealintubationofgeneralanesthesiainduction.Methods124patientswhowerescheduledforelectivesurgeryandrequiredendotrachealintubationwererandomlydividedintotwogroups,with62casesineachgroup,theyweregivenintravenou
5、sinjectionofMidazolam0.1mg/kg,Fentanyl3ug/kgforanesthesiainduction.ThentheCisatracuriumgroupwasgivenCisatracurium0.15mg/kg,andRocuroniumgroupwasgivenRocuronium0.6mg/kg,Sevofluranewasusedtocontrolanesthesiadepthafterendotrachealintubation.Thetotaleffectiverateandchangesofe
6、ndotrachealintubationcondition,MAP,Sp02andHR5minafterintubationinthetwogroupswerecomparedbeforeendotrachealintubationandaftergeneralanesthesiainduction.Besides,theclinicalonsettime,musclerelaxanteffecttime,musclerecoveryindexandadversereactionswerealsoobserved.ResultsTota
7、leffectiverateoftheRocuroniumgroup(95.2%)forendotrachealintubationwashigherthanthatoftheCisatracuriumgroup(88.6%),thedifferencewasstatisticallysignificant(x2=1.74,P[Keywords]Endotrachealintubation;Cisatracurium;Rocuronium;Onsettime选择适当的肌松药物,以谋求最佳的气管插管条件和肌松恢复效果是临床麻醉研究的重点之一
8、[1-2]。顺式阿曲库皱和罗库漠钱均为临床上使用较多的麻醉肌松药,本研究对它们用于气管插管患者的条件进行了临床研究,旨在为临床全麻诱导时肌松药的合理选择提供参考。现报道如下:1资料与方法1.1