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时间:2020-05-20
《小细胞肺癌化疗前后PXR和MDR1在外周血单个核细胞中的表达及意义.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、现代肿瘤医学2014年12月第22卷第12期MODERN0Nc0L0GY,Dec.2014,VOL.22,NO.12·2867·[J].实用肿瘤学杂志,2012,26(1):11—17.徐建宇.局部晚期非小细胞肺癌不同放化疗模式的临床研究[7]ArrietaOBlakeM,DelaMata—Moya.Phase1study.Concurrent[D].哈尔滨:哈尔滨医科大学,2009.chemotherapyandradiotherapywithnitroglycerininlocallyad—GrahamPH,ClarkC,AbellF,eta1.Concurrentend—pha
2、seboostvancednon—smallcelllungcancer[J].RadiotherOncol,2014,26high—doseradiationtherapyfornon—small—celllungcancer(1):25—28.withorwithoutcisplatinchemotherapy[J].AustralasRadiol,[8]CrvenkovaS,KrstevskaV.Sequentialchemoradiotherapycompared2006,50(4):342—348.withconcurrentchemoradiotherapyinlocal
3、lyadvancednon—smallBelaniCP,ChoyH,BonomiP,eta1.Combinedchemoradiotherapycelllungcancer:Ourexperience[J].Prilozi,2009,30(2):197—regimensofpaclitaxelandearboplatinforlocallyadvancednon—207.smallcelllungcancer:ArandomizedphaseIIlocallyadvanced[9]熊勇,周同冲,刘源,等.多西他赛联合顺铂同步放化疗治疗局multi—modalityprotocol[J
4、].JClinOncol,2005,23(25):5883部晚期非小细胞肺癌的疗效分析[J].中华肿瘤防治杂志,—5891.2010,9(17):699—702.张真,韩淑红,张小涛,等.局部晚期非小细胞肺癌同步放化疗[1O]金和坤,罗荣喜.诱导化疗加同步放化疗与单纯同步放化疗治联合巩固化疗或诱导化疗的随机I临床研究[J].医学研究杂疗局部晚期非小细胞肺癌的临床疗效比较[J].中外医疗,志,20o9,38(3):64—67.2008,27(16):44—45.(编校:张西教)rLrLrL[⋯小细胞肺癌化疗前后PxR和MDR1在外周血单个核细胞中的表达及意义左晓丽,孔庆暖,纪霞,韩增磊
5、,卫红军,黄雏清SignificanceofPXRandMDR1expressioninperipheralbloodmononuclearcellsofsmallcelllungcancerbeforeandafterchemotherapyZuoXiaoli,KongQingnuan,JiXia,HanZenglei,WeiHongjun,HuangWeiqingDepartmentofPathology;DepartmentofRespiratoryMedicine,MedicalCollegeofQingdaoUniversityAfiliatedQingdaoMunicip
6、alHos—pital,ShandongQingdao266071,China.【Abstract】Objective:ToinvestigatetheexpressionofpregnaneXreceptor(PXR)andmultidmgresistantprotein一1(MDR1)inperipheralbloodmononuclearcells(PBMCs)ofsmallcelllungcancerpatientsandtheirrelationshipbeforeandafterchemotherapy.Methods:A1l43casesofsmallcelllungc
7、ancerpatientsand20casesnormalcontrolswereinvolvedinthisstudy.Afterseparatedbycentrifuge,combiningwiththinprepcytologictest,immunohistochemicalmethodswereusedtostudytheexpressionofPXRandMDR1inPBMCs.Results:TheexpressionofPXRandMDR1
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