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时间:2020-05-15
《甲状腺良性结节单侧腺叶切除术后血清T3、T4、TSH的变化及临床意义.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·842·西部医学2014年7月第26卷第7期MedJWestChina,July2014,Vo1.26,No.7甲状腺良性结节单侧腺叶切除术后血清T3、T4、TSH的变化及临床意义*柯章明,汤彪,孙圣荣,叶财盛。(1.鄂州市中心医院普外科,湖北鄂州436000;2.武汉大学人民医院乳甲外科,湖北武汉430060;3.中山大学附属第一医院甲状腺外科,广东广州510080)【摘要】目的探究甲状腺良性结节患者行单侧腺叶切除术后血清T3、T4及TSH等的变化情况。方法选取2010年3月一2012年5月来院就诊的l1O例行单侧腺叶切除术的甲状腺良性结节患
2、者,依据患者的年龄分为老年组(年龄≥6O岁)62例及中青组(年龄<6O岁)48例;依据患者术前的促甲状腺激素(TSH)分为较低组(TSH≤1.6mIU/L)67例及较高组(TSH>1.6mIU/L)43例。分别于术前及术后3个月抽取患者的静脉血检测其血清T3、T4、fT3、fT4水平。结果治疗前各组指标比较均未见明显差异(P>0.05);治疗后3个月老年组患者的fT4较中青组明显下降(P3、但老年患者及基础TSH较高患者的代偿能力较差,一般需要给予药物替代治疗。【关键词】甲状腺良性结节;单侧腺叶切除;年龄;促甲状腺素水平;甲状腺功能【中图分类号】R581.3【文献标志码】Adoi:10.3969/J.issn,1672-3511.2014.07.009TheclinicalsignificanceofserumT3,T4,TSHonpatientswithBenignthyroidnodulesafterunilaterallobectomyKEZhang-ming,TANGBiao,SUNShen-ron~,etnf(1.Depa4、rtmentofGeneralSurgery,EzhouCentralHospital,Ezhou436000,Hubei;2.DepartmentofBreastSurgery,ThePeople~HospitalofWuhanUniversity,Wuhan430060;3.DepartmentofThyroidSurgery,TheFirstAfftliatedHospitalofSunYat—SenUniversity,Guangzhou510080)[Abstract]ObjectiveToexploretheclinicalsigni5、ficanceofserumT3,T4,TSHonbenignthyroidnodulespa—tientsafterunilatera11obectomy.MethodsI10benignthyroidnodulespatientswereinvolvedinthepresentstudy.Thepatientsweredividedintoeldergroup(Age≥60years,一62cases)andyoungergroup(age~60years,一48cases),ac。cordingtOage.Thepatientsweredi6、videdintothelowergroup(TSH≤1.6mIU/L,,l=67cases)andthehighergroup(TSH>1.6mIU/L,n=43cases)accordingtOthelevelsofthyrotropin(TSH).TheserurD.T3,T4,fT3,fT4levelsafteroperationand3monthsafteroperationweredetectedandcompared.ResultsThedifferenceofindexeswasnotsignifi—cantbeforetreat7、ment(P>O.05).3monthsaftertreatment,thelevelsoffT4oftheoldergroupdecreasedsignificantlycomparedwiththeyoungergroup(P8、ntsofthecontralatera1thyroidglandofthepatientswithunilateralthyroidl
3、但老年患者及基础TSH较高患者的代偿能力较差,一般需要给予药物替代治疗。【关键词】甲状腺良性结节;单侧腺叶切除;年龄;促甲状腺素水平;甲状腺功能【中图分类号】R581.3【文献标志码】Adoi:10.3969/J.issn,1672-3511.2014.07.009TheclinicalsignificanceofserumT3,T4,TSHonpatientswithBenignthyroidnodulesafterunilaterallobectomyKEZhang-ming,TANGBiao,SUNShen-ron~,etnf(1.Depa
4、rtmentofGeneralSurgery,EzhouCentralHospital,Ezhou436000,Hubei;2.DepartmentofBreastSurgery,ThePeople~HospitalofWuhanUniversity,Wuhan430060;3.DepartmentofThyroidSurgery,TheFirstAfftliatedHospitalofSunYat—SenUniversity,Guangzhou510080)[Abstract]ObjectiveToexploretheclinicalsigni
5、ficanceofserumT3,T4,TSHonbenignthyroidnodulespa—tientsafterunilatera11obectomy.MethodsI10benignthyroidnodulespatientswereinvolvedinthepresentstudy.Thepatientsweredividedintoeldergroup(Age≥60years,一62cases)andyoungergroup(age~60years,一48cases),ac。cordingtOage.Thepatientsweredi
6、videdintothelowergroup(TSH≤1.6mIU/L,,l=67cases)andthehighergroup(TSH>1.6mIU/L,n=43cases)accordingtOthelevelsofthyrotropin(TSH).TheserurD.T3,T4,fT3,fT4levelsafteroperationand3monthsafteroperationweredetectedandcompared.ResultsThedifferenceofindexeswasnotsignifi—cantbeforetreat
7、ment(P>O.05).3monthsaftertreatment,thelevelsoffT4oftheoldergroupdecreasedsignificantlycomparedwiththeyoungergroup(P8、ntsofthecontralatera1thyroidglandofthepatientswithunilateralthyroidl
8、ntsofthecontralatera1thyroidglandofthepatientswithunilateralthyroidl
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