欢迎来到天天文库
浏览记录
ID:55397778
大小:240.22 KB
页数:3页
时间:2020-05-15
《黄芪注射液对脾切除术后早期T细胞亚群的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、182肝胆外科杂志2015年6月第23卷第3期JournalofHepatobiliarySurgery,Vol,23,No.3,Jun.2015黄芪注射液对脾切除术后早期T细胞亚群的影响石秀全,强泽好【摘要】目的观察中药黄芪注射液对外伤性脾破裂行脾切除患者手术前、后外周血T淋巴细胞亚群的变化。方法选50例外伤性脾破裂需要行脾切除病例,随机分实验组、对照组,每组各25例。用免疫荧光法检测脾切除患者手术前、术后第1、3、7d测定T细胞亚群CD3、CD4、CD8数值水平,分别记录实验组、对照组切El感染、肺部感染、术后低热的发生率。结果实验组、对照组术前外周血C
2、D3、CD4、CD8水平比较无统计学意义。脾切除术后第1d,CD3、CD4、CD8水平较手术前比较,两组均有降低,组间比较无统计学意义;但实验组第3d呈升高趋势,且第7d仍然保持在较高水平。对照组第3d即下降,第7d与第3d比较,变化无统计学意义。两组在术后第3d开始,CD3、CD4、CD8数据比较即有明显差异(P<0.05)。结论黄芪注射液对脾切除术后早期T细胞亚群CD3、CIM、CD8水平的变化,具有一定影响,对脾切除术后免疫功能的提高、术后并发症的减少,具有较好的疗效,可以作为脾切除术后中西医结合提高患者免疫功能的一种治疗手段。【关键词】创伤性脾破裂;
3、脾切除;黄芪注射液;T细胞亚群;免疫功能【中图分类号】R659【文献标识码】A【文章编号】1006-4761(2015)01-0182-03EfectsofHuangqiinjectionaftersplenectomyearlyTcellsubsets(SillXiuquan,QIANGZe—hao.ThePeopleSHospitalofYinshang,Yinshang236200,China)【Abstract】ObjectiveObservedbeforetraumaticruptureoftraditionalChinesemedicineHua
4、ngqiinjectiononpatientsunder—goingsplenectomyafterperipheralbloodTlymphocytesubsets.Method50casesoftraumaticruptureoftheneedsplenectomypatientswererandomlydividedintoexperimentalgroupandcontrolgroup,25casesineachgroup.Byimmunofluorescenceassaybeforesplenecto—mysurgerypatients,posto
5、perativel,3,7daymeasuredTcellsubsetsCD3,CD4,CD8numericalleve1.Wererecordedintheexpefi—mentalgroupandcontrolgroupwoundinfection,pulmonaryinfection,theincidenceofpostoperativefever.Resultstheexperimentalgroup,controlgrouppreoperativepefipheralbloodCD3,CIM,CD8levelwasnotstatisticallys
6、ignificant.SplenectomySectionpostoper-ativelday,CD3,CD4,CD8levelsthanbeforethesurgerycomparedbothgroupsdecreasedbetweenthetwogroupswasnotstatisticallysignificant;However,theexperimentalgroupshowedanincreasingtrendafteroperative3day,andtheafteroperative7dayremainedatahighleve1.after
7、operative3daycontrolgroupthatdropped,andtheafter7day、3daycomparisonwiththeTcellchangewasnotstatisti—callysignificant。Thetwogroupsbeganinthe3daysaftersurgery,CD3,CD4,CD8datacomparisonsthatweresignificantlydifferent(P<0.05).ConclusionHuangqiinjectiononsplenectomyearlyTcellsubsetsCD3,
8、CD4,CD8levelchanges,Hasace
此文档下载收益归作者所有