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时间:2020-05-12
《地佐辛在全麻诱导气管插管中的应用价值.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、第32卷第2期(第25页)湖北民族学院学报·医学版V01.32No.2P.252015正JournalofHubeiUniversityforNationalities·MedicalEdition2015地佐辛在全麻诱导气管插管中的应用价值王琦南京医科大学附属江宁医院(江苏南京211100)【摘要】目的探讨地佐辛在全麻诱导气管插管中的应用价值。方法筛选2013年1月至2014年6月于我院进行全麻择期手术患者106例,采用随机数表法将其分为试验组与对照组,每组53例,其中试验组患者于全麻诱导前静脉给予5mg地佐辛行超前镇静,对照组同期
2、静脉给予1mL生理盐水,比较两组患者的麻醉效果及不良反应发生情况。结果试验组患者地佐辛注人后10min呼吸频率明显较对照组及注人前加快(P0.05),与对照组比较存在显著差异(P<0.05);试验组患者全麻丙泊酚用量明显低于对照组(P<0.05),并且试验组术后各时期VAS评分均低于对照组(P<0.05);两组患者不良反应发生率比较无显著差异(P>O.05)。结论地佐辛作为全麻手术超前镇痛药物具有较好的术中镇痛、镇静效果,可降
3、低全麻药物的应用剂量,并有利于稳定患者术中血流动力学指标,具有临床应用及推广价值。【关键词】地佐辛;全麻诱导;气管插管;应用价值【中图分类号】R614【文献标识码】A【文章编号】1008-8164(2015)02—0025—02TheApplicationValueofDezocineonEndotrachealIntubationunderInductionofGeneralAnesthesiaWANGQi(JiangningHospitalAfiliatedtoNanjingMedicalUniversity,Nanjing211
4、100,China)【Abstract】ObjectiveTostudytheapplicationvalueofDezocineonendotrachealintubationun—derinductionofgeneralanesthesia.Methods106casesundergoingselectiveoperationandgen—eralanesthesiabetweenJanuary2013andJune2014inourhospitalwereselectedasthere—searchobject.106case
5、swouldbedividedintoexperimentalgroupandcontrolgroupbyusingstochasticway,53casesineachgroup.Theexperimentalgroupwasinjectedwith5mgDezo-cineandacceptedpreemptiveanalgesiabeforegeneralanesthesiainductionwhilethecontroIgroupwasgivenlmlsalineviaveinpump.Wewouldcomparetheanes
6、thesiaeffectsandad-versereactionsintwogroups.ResultsThebreathfrequencyoftheexperimentalgroupat10minafterDezocineinjectionwasobviouslyfasterthanthatofthecontrolgroupandbefore.Com—paredwithbeforeanesthesiainduction,theSBPandDBPoftheexperimentalgrouphadnosig—nificantdiffer
7、enceat5minafterendOtracheaIintubationbuthadmoredifferencethanthoseofthecontrolgroup(P<0.05).Thedosageofgeneralanesthesiapropofoloftheexperimentalgroupwassignificantlylowerthanthatofthecontrolgroup,andtheVASscoreswerelowerthanthoseofthecontrolgroupatpostoperativeperiods(
8、PO.05).ConclusionsDezocineaspreemptiveanalg
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