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ID:55162084
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时间:2020-04-29
《非酒精性脂肪肝与代谢综合征相关指标变化研究.doc》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、非酒精性脂肪肝与代谢综合征相关指标变化研究 Studyonrelatedindexeschangesofnon-alcoholicfattyliverdiseaseandmetabolicsyndromeLIWei-lan,ZHOUYing,PANChun-mei.SouthChinaAgriculturalUniversityHospital,Guangzhou510642,China 【Abstract】ObjectiveToexplorethecorrelationbetweennon-alcoholicfattyliverdiseasepr
2、evalencesituationandmetabolicsyndromerelatedindexeschanges.MethodsCompletemedicalinformationof3071faultymemberswascollectedtoanalyzecorrelationbetweenNAFLDandlipidmetabolismdisorders,hypertension,hyperglycemia,hypeluricemialevel,andNAFLDprevalencesituationwasstudiedindifferentag
3、eandgender.ResultsAmong3071cases,therewere1022NAFLDcases,withprevalenceraterateas33.28%.Theincidenceofdiseaserisingwithage,andmalehadhigherNAFLDprevalenceratethanfemale.Thedifferencehadstatisticalsignificance.NAFLDgrouphadobviouslyhigherprevalencerateoflipidmetabolismdisorders,h
4、ypertension,hyperglycemia,hypeluricemialevelthannonNAFLDgroup,andthedifferencehadstatisticalsignificance.NAFLDgrouphadobviouslyhigherbodymassindex,systolicbloodpressure,diastolicbloodpressure,triglyceride,totalcholesterol,highdensitylipoproteincholesterol,lowdensitylipoproteinch
5、olesterin,fastingblood-glucose,alanineaminotransferaseanduricacidlevelthannonNAFLDgroup,andtheirdifferencehadstatisticalsignificance.NAFLDgrouphadORvalueofTGas1.523,BMIas1.325,FBGas1.156andDBPas1.429.BMI,FBG,TGandDBPtestvaluewereobviouslycorrelatedtoNAFLD.ConclusionNAFLDoccurren
6、cewasnotonlycorrelatedtolipidmetabolismdisorders,butalsocloselycorrelatedtoage,genderandsystemicdiseaseofhyperlipidaemia,hypertension,hyperglycemiaandhypeluricemia. 【Keywords】Non-alcoholicfattyliverdisease;Metabolicsyndrome �S着人们生活水平的提高以及饮食结构的变化,NAFLD的发病率呈日益增长的趋势,已成为人们普遍关注的一个公
7、共健康问题[1]。本研究收集了某高校2016年10月3071例教职工的体检完整资料,调查其NAFLD患病现状,分析NAFLD与高脂血症、高血压、高血糖、高尿酸等多种代谢紊乱的全身性疾病的变化关系。具体报告如下。 1资料与方法 1.1一般资料选取2016年10月某高校体检资料完整的3071例教职工作为研究对象,其中男1470例,女1601例,年龄22~90岁。纳入标准:①无饮酒史或酒量不过量;②出现乏力、腹胀、肝区隐痛等症状,可伴肝、脾肿大;③以ALT为主的血清转氨酶升高,可伴有谷胺酰转肽酶、TG等水平增高;④肝脏超声检查符合弥漫性脂肪肝。排除标准:
8、①过量饮酒者;②慢性病毒性肝炎史、代谢异常和药物等引起的肝病;③全胃肠外营养史;④甲状腺功能亢
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