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时间:2020-05-24
《非酒精性脂肪性肝病与代谢综合征相关性研究.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·1062·中华流行病学杂志2014年9YJ第35卷第9期ChinJEpidemiol,September2014,Vo1.35,No.9·『I床研究·非酒精性脂肪性肝病与代谢综合征相关性研究胡卫张苗旋谭金海【摘要】目的分析非酒精性脂肪性肝病(NAFLD)与MS的相关性。方法2010-2011年对武汉大学医院在校教职工体检包括询问病史、体格检查、生化检查、肝脏彩超检查。按NAFLD诊断标准将研究对象分为NAFLD组和非NAFLD组,对两组与MS及其相关因素进行比较分析。结果(1)NAFLD总患病率为20.7%,MS为13.3%,NAFLD组BMI、SBP、DBP、TG、FPG均较非NAFLD组
2、高,HDL—C水平低于非NAFLD组(P3、ndmetabolicsyndromeHuWe.ZhangMiaoxuan.nJinhai.HospitalofWuhanUniversity。Wuhan430072。ChinaCorrespondingauthor:TanJinha,Email:2410746045@qq.corn【Abstract】0bjectiveToanalyzetherelationbetweennonalcoholicfattyliverdisease(NAFLD)andmetabolicsyndrome(MS)amongadultsfromtheFunctionalUniversitySociety(FUS).M4、ethodsThissurveywasconductedamongthestafofWuhanUniversitywhounderwentphysicalcheck.upsfrom2010to2Ol1attheAffiliatedHospitalofWuhanUniversity.Thepattieipantshadrecordsrelatedtomedicalhistory,clinica1examination,anthropometry,1aboratorytestsandroutineliverultrasonography.Accordingtothediagnosticcriter5、iaofNAFLD.thecasesweredividedintotwogrOups—withNAFLDorwithout.MSanditsrelevantriskfactorsofthetwogroupswerecompared.Results1)TheprevalenceratesofnonalcoholicfattyliverdiseaseandMSwere20.7%.andl3-3%,respectively.PeoplewithnonalcoholicfattyliverdiseasehadhigherlevelsofBMI。SBP,DBP,TG。FPGand1owerlevelof6、HDL—Cthanthosewhodidnothavetheproblem.2)TherisksofNAFLDgroupindevelopingMS。obesity.hypertensionanddyslipidemiawerehigherthanthenon—group(P<0.001).3)TheNAFLDgrouphad1.66,4.22,8.72and25.62timeschancesofhaving1to4riskfactorsonMSthanthosewithoutNAFLD.ConclusionNAFLDwascloselyassociatedwithMSanditsreleva7、ntriskfactors.【Keywords】Nonalcoholicfattyliverdisease;Metabolicsyndrome;Relativityanalysis非酒精性脂肪性肝病(NAFLD)和MS患病率目名教工体检资料中,剔除患自身免疫性肝炎和肝硬前呈现明显上升趋势,普遍的观点认为NAFLD是化、继发性高血压、血吸虫病史者,并排除有长期饮MS的一种肝脏表现。为分析NAFLD与
3、ndmetabolicsyndromeHuWe.ZhangMiaoxuan.nJinhai.HospitalofWuhanUniversity。Wuhan430072。ChinaCorrespondingauthor:TanJinha,Email:2410746045@qq.corn【Abstract】0bjectiveToanalyzetherelationbetweennonalcoholicfattyliverdisease(NAFLD)andmetabolicsyndrome(MS)amongadultsfromtheFunctionalUniversitySociety(FUS).M
4、ethodsThissurveywasconductedamongthestafofWuhanUniversitywhounderwentphysicalcheck.upsfrom2010to2Ol1attheAffiliatedHospitalofWuhanUniversity.Thepattieipantshadrecordsrelatedtomedicalhistory,clinica1examination,anthropometry,1aboratorytestsandroutineliverultrasonography.Accordingtothediagnosticcriter
5、iaofNAFLD.thecasesweredividedintotwogrOups—withNAFLDorwithout.MSanditsrelevantriskfactorsofthetwogroupswerecompared.Results1)TheprevalenceratesofnonalcoholicfattyliverdiseaseandMSwere20.7%.andl3-3%,respectively.PeoplewithnonalcoholicfattyliverdiseasehadhigherlevelsofBMI。SBP,DBP,TG。FPGand1owerlevelof
6、HDL—Cthanthosewhodidnothavetheproblem.2)TherisksofNAFLDgroupindevelopingMS。obesity.hypertensionanddyslipidemiawerehigherthanthenon—group(P<0.001).3)TheNAFLDgrouphad1.66,4.22,8.72and25.62timeschancesofhaving1to4riskfactorsonMSthanthosewithoutNAFLD.ConclusionNAFLDwascloselyassociatedwithMSanditsreleva
7、ntriskfactors.【Keywords】Nonalcoholicfattyliverdisease;Metabolicsyndrome;Relativityanalysis非酒精性脂肪性肝病(NAFLD)和MS患病率目名教工体检资料中,剔除患自身免疫性肝炎和肝硬前呈现明显上升趋势,普遍的观点认为NAFLD是化、继发性高血压、血吸虫病史者,并排除有长期饮MS的一种肝脏表现。为分析NAFLD与
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