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《慢性乙型肝炎抗病毒治疗依从性影响因素分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·126·国际病毒学杂志2014年6月第2l卷第3期InternationalJournalofVirology,Jun.2014,Vo1.21,No.3慢性乙型肝炎抗病毒治疗依从性影响因素分析苌华颖孙利红王晓才【摘要】目的探讨慢性乙型病毒性肝炎患者用药依从性的影响因素。方法以服药依从性差的32例患者为观察组;服药依从性好的32例患者为对照组。采用Logistic回归分析方法,探索影响慢性乙型肝炎患者服药依从性的因素。结果与服药依从性差的患者相比,服药依从性好的患者组中有乙肝家族史(OR0.042,95%C.I.0.005~0.333)、抗病毒治疗的
2、认知程度高(OR0.112,95%C.I.0.014~0.872)和“医师告知”详细(OR0.142,95%C.I.0.020~0.993)的出现服药依从性差的危险度均降低。结论有乙肝家族史的患者,可从亲属的诊疗经历中获得经验,而服药依从性较好。此外,医师加强对患者“治疗认知度”的培训,可提高患者抗病毒治疗的依从性。【关键词】慢性乙型病毒性肝炎;抗病毒治疗;治疗认知度;依从性AnalysisoninfluencefactorsofantiviraltherapycomplianceinchronichepatitisBcasesCHANGHua—yi
3、ng,SUNLi—hong,WANGXiao—cai.OrientalHospitalofBeijingUniversityofChineseMedi—cine,Beijing100078,China.Correspondingauthor:CHANGHua—ying,Email:changhy79@sina.COrn【Abstract】OhjectiveToanalyzethefactorswhichinfluencedmedicationcomplianceofpatientswithchronichepatitisB(CHB),SOastoim
4、provethetreatmentcomplianceofpatients.Methods32pa—tientswithpoorcompliancewererecruitedastheobservationgroup,32patientswithgoodcompliancewereselectedasthecontrolgroup.Themultivariatelogisticregressionmodelwasusedtoinvestigatethepotentialcorrelativefactorsthatinfluencedthemedica
5、tioncomplianceofthecase.ResultsComparedwithpoorreed—icationcomplianceofpatients,thegoodmedicationcomplianceofpatients,whohadfamilyhistoryofhepati—tisB(OR0.042,95%C10.005-0.333),learnedmoreaboutthecontentoftheantiviraltreatment(OR0.112,95%C10.014-0.872),andgotmoreinformationfrom
6、physicians(OR0.142,95%C10.020—0.993),showedpoorcomplianceriskreduction.ConclusionsThepatientswhohadfamilyhistoryofhep—atitisBcangainmoremessagefromtherelativeexperienceoftreatment.Theirmedicationcompliancewerebetter.Futureworkshouldfocusonhealtheducationtoimprovethecomplianceof
7、patientsreceivingantiviraltherapy.【Keywords1ChronicviralhepatitisB;Antiviraltherapy;Treatmentofcognition;Compliance慢性乙型病毒性肝炎(chronichepatitisB,接影响治疗效果,造成乙型肝炎病毒(hepatitisBv1一CHB)严重危害人体健康。我国现有CHB患者约Ills,HBV)病毒学突破,而发生耐药,导致病情反2000万例¨。核苷(酸)类似物因其服用方便、患者复,甚至发展成重型肝炎而危及生命[2]。本研究对耐受性好等原因
8、,是目前临床治疗CHB的常用抗病门诊接受抗病毒治疗的患者进行调查,分析影响患毒药物。核苷(酸)类似物要求患者
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