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时间:2020-05-07
《乙醇对实验大鼠精浆生化指标的相关性影响研究-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、基础研究Jichuyanjiu《中国医学创新》第11卷第25期(总第307期)2ol4年9fl乙醇对实验大鼠精浆生化指标的相关性影响研究陈杰翔①李利①【摘要】目的:建立慢性饮酒实验大鼠模型,测定精浆生化(ot一葡萄糖苷酶、酸l生磷酸酶、精浆果糖、精浆锌)的含量变化,探讨不同酒精含量对大鼠精浆生化的影响。方法:将4O只健康雄性成年sD大鼠随机分为四组,其中对照组给予蒸馏水灌胃,酒精组分别给予无水酒精0.5∥(kg·d)、2.5(kg·d)、5g,(kg·d)灌胃,连续2O周。测定各组实验大鼠精浆生化(ot一葡萄糖苷酶、酸性磷酸酶、精浆果糖、精浆锌)的含量变化。结果:各酒精组实验大
2、鼠精浆生化指标均明显低于正常对照组,差异均有统计学意义(P3、(25):016-018【Abstract】Objective:Toestablishexperimentalratmodelofchronicethanolingestionandmeasureseminalplasmabiochemistry(仅-glucosidase,acidphosphatase,seminalfructose,seminalzinc)content,andtoexploretheefectsofdiferentalcoholcontentofseminalplasmabiochemicalrats.Method:40healthySprague-Da4、wleyadultmaleratswererandomlydividedintofourgroups.Thecontrolgroupwasgivendistilledwater,diferentdosesofalcohol0,5(kg·d)。2.5g,(kg‘d),5(kg‘d)wereadministratedtotheratsofalcoholgroupfor20weeksbygavage.Thecontentchangeofseminalplasmabiochemistry(-glueosidase,acidphosphatase,seminalfructose,semi5、nalzinc)inallexperimentalratsweredetermined.Result:Seminalplasmabiochemicalindicatorsofeachalcoholgroupratswassignificantlylow@rthanthecontrolgroup,thedifferenceswerestatisticallysignificant(P6、seratsgroup。thediferenceswerestatisticallysignificant(P<0.05orP7、inalmovement[J].MethodsEnzymol,2012,514(1):52(5):416—420.289—301.[14]章丽金,郑晓玲,林志辉,等.胃动索与青壮年胆汁反流的关【11】YanCL,WangSB,JiangZY.TheeffectofmotilininPVNof系探讨[J】.中国医学创新,2011,8(29):144—146.hypothalamusonthegastricmotility[J].ChineseJournalofApplied【15】Deorte
3、(25):016-018【Abstract】Objective:Toestablishexperimentalratmodelofchronicethanolingestionandmeasureseminalplasmabiochemistry(仅-glucosidase,acidphosphatase,seminalfructose,seminalzinc)content,andtoexploretheefectsofdiferentalcoholcontentofseminalplasmabiochemicalrats.Method:40healthySprague-Da
4、wleyadultmaleratswererandomlydividedintofourgroups.Thecontrolgroupwasgivendistilledwater,diferentdosesofalcohol0,5(kg·d)。2.5g,(kg‘d),5(kg‘d)wereadministratedtotheratsofalcoholgroupfor20weeksbygavage.Thecontentchangeofseminalplasmabiochemistry(-glueosidase,acidphosphatase,seminalfructose,semi
5、nalzinc)inallexperimentalratsweredetermined.Result:Seminalplasmabiochemicalindicatorsofeachalcoholgroupratswassignificantlylow@rthanthecontrolgroup,thedifferenceswerestatisticallysignificant(P6、seratsgroup。thediferenceswerestatisticallysignificant(P<0.05orP7、inalmovement[J].MethodsEnzymol,2012,514(1):52(5):416—420.289—301.[14]章丽金,郑晓玲,林志辉,等.胃动索与青壮年胆汁反流的关【11】YanCL,WangSB,JiangZY.TheeffectofmotilininPVNof系探讨[J】.中国医学创新,2011,8(29):144—146.hypothalamusonthegastricmotility[J].ChineseJournalofApplied【15】Deorte
6、seratsgroup。thediferenceswerestatisticallysignificant(P<0.05orP7、inalmovement[J].MethodsEnzymol,2012,514(1):52(5):416—420.289—301.[14]章丽金,郑晓玲,林志辉,等.胃动索与青壮年胆汁反流的关【11】YanCL,WangSB,JiangZY.TheeffectofmotilininPVNof系探讨[J】.中国医学创新,2011,8(29):144—146.hypothalamusonthegastricmotility[J].ChineseJournalofApplied【15】Deorte
7、inalmovement[J].MethodsEnzymol,2012,514(1):52(5):416—420.289—301.[14]章丽金,郑晓玲,林志辉,等.胃动索与青壮年胆汁反流的关【11】YanCL,WangSB,JiangZY.TheeffectofmotilininPVNof系探讨[J】.中国医学创新,2011,8(29):144—146.hypothalamusonthegastricmotility[J].ChineseJournalofApplied【15】Deorte
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