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1、HainDllMedJ,Oct.2013,Vo1.24。No.20海南医学2013年l0月第24卷第20期doi:10.3969/j.issn.1003—6350.2013.20.1248·论手术切除加术中温水浴疗治疗肝癌的临床研究梁安林,李灼日,周开伦,郑进方,张震生,邢贻雷,武金才,孙启刚,陈家诚(海南省人民医院肝胆外科,海南海口570311)【摘要】目的探讨手术切除加术中温水浴疗治疗肝癌的安全性及I临床应用的意义。方法回顾我院2010年6月至2013年6月手术切除治疗肝癌73例,随机分成两组,A组37例(研究组)采取手术切除加术中温水浴疗治
2、疗,B组(对照组)36例采取单纯手术切除治疗。比较两组的手术前后免疫功能变化、术后并发症、死亡率、恢复时间、复发率、生存率以及治疗费用等指标差异。结果两组在术后并发症、死亡率、术后恢复时间及治疗费用方面相似,差异无统计学意义(P>O.05),但在免疫功能变化方面两组差异显著,具有统计学意义(P<0.05),研究组术后复发率较对照组低,而生存率较对照组高,两者间差异具有统计学意义<0.05)。结论手术切除加术中温水浴疗是一种安全、有效的肝癌综合治疗方法,其具有操作简单、价格便宜、微创或无创的特点,值得推广应用。【关键词】切除,温水浴疗,肝癌【中图分
3、类号】R735.7【文献标识码】A【文章编号】1o03—635O(20l3)2O一2993—O2ClinicalappficafionofexcisioncombinedwitllwarmbaththerapyinthetreatmentofHvercancer.HANGAn—lin,LIZhuo—ri,ZHOUKai-lun,ZHENGAt-fang,ZHANGZhen-sheng,XINGYi-lei,WUJin--cai,SUNQi-gang,CHENJia--cheng.DepartmentofHepatobiliarySurgery,t
4、hePeopleHospitalofHainanProvince,Haikou570311,Hainan,CHINA【Abstract】ObjectiveToinvestigatethesafetyandsignificanceofexcisioncombinedtIlwarmbaththera—pyinthetreatmentoflivercancelMethodsTheclinicaldataof73patientswithlivercancerinourhospitalfromJune2010toJune2013wasretrospecti
5、velyanalyzed.Thepatientswererandomlydividedintotwogroups:groupA(n=37,excisioncombinedwithwarnlbaththerapy),groupB(36,excision).Thechangeofimmunologicfunctionbeforeandaftersurgery,postoperativecomplications,mortality,recoverytime,therecurrencerate,survivalrate,andthecostoftrea
6、tmentbetweenthetwogroupswerecomparedandanalyzed.ResultsTherewasnostatisticallysignifi-cantdiferencebetweenthetwogroupsinpostoperativecomplications,mortality,postoperativerecoverytimeandcostoftreatment(P>0.05),butthechangesofimmunologicfunctionshowedstatisticallysignificantdif
7、erence(P<0.05).Comparedwimthecontrolgroup.therecurrencerateinstudygroupwassignificantlylower,andthesurvivalratewassignificantlyhigher(P<0.05).ConclusionExcisioncombinedwithwarmbaththerapyisasafe,efectivecompre—hensivetreatmentinlivercancer,whichhasthecharacteristicsofoperates
8、imply,inexpensive,minimallyinvasiveornon-invasive.Itshouldbewidelyap