中西医结合治疗晚期血吸虫性肝硬化腹水-论文.pdf

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1、合临床2014年7月第14卷第7·11·中西医结合治疗晚期血吸虫性肝硬化腹水刘烈全张军田岳霄胡恒汪刚(湖北省荆州市第三人民医院荆州434000)摘要：目的：探索西药联合桃红四物汤加减治疗晚期血吸虫性肝硬化腹水的效果。方法：将68例晚期血吸虫性腹水型患者随机分为对照组和治疗组各34例，对照组采取休息、限钠、限水、护肝、利尿、输注白蛋白及支持等治疗，治疗组在对照组基础上予桃红四物汤治疗，中药治疗持续3--6个月。两组均治疗15d和30d后进行疗效对比，并观察症状和体征、肝肾功能及电介质、腹水复发情况(每3个月随访1次)及肝纤维化指标。结果：治疗1

2、5d后治疗组总有效率为73．5％，对照组总有效率为50．O％，两组总有效率有显著性差异(P0．05)，但显效率有显著性差异(PO．05)；治疗组腹水复发时间平均23．2个月，对照组平均16．3个月，治疗组复发时间明显延长(P

3、血吸虫性腹水疗效优于单纯西药治疗。关键词：晚期血吸虫病：肝硬化腹水：桃红四物汤IntegratedTCMandWMTreatmentforAdvancedLIULie-quan，ZHANGJun，TIANYue-xiao，HUHeng,WANGGang(TheThirdHospitalofJingzhou，Hubei434000)Abstract：Objective：ToexploretheclinicalefectofwesternmedicinecombinedwithTaohongsiwudecoctionforadvancedSchi

4、stosomiasis-inducedcirrhosisascites．Method：68Patientswithadvancedschistosomiasisasciteswererandomlydividedintotwogroups，thetreatmentgroupandthecontrolgroup，eachgroupconsistingof38cases．Patientsincontrolgroupweresubjectedtorest，limitedsaltandwaterintake，andsupportivemeasures

5、toprotectliver，facilitateurination，andinjectalbumin，etc．Patientsintreatmentgroup，besidesthemeasuresappliedtopatientsincontrolgroup，werecontinuouslyadministeredTaohongsiwudecoctionfor3--6months．After15daysand30days，symptomsandphysicalindicatorsofpatientsinbothgroups，suchasli

6、verandrenalfunction，electrolyte，relapseofascitesandliverfibrosislevel，wererespectivelyobservedandcompared(withafollow-upvisitevery3months)．Results：After15days，t0talefectiverateoftreatmentgroupreached73．5％，andthefigureofcontrolgroupstood50．O％，thediferencebetweenthetwogroupsw

7、asstatisticallysignificant(P<0．05)．After30days，21patientsintreatmentgroupwitnessedsignificantrecovery,and7showedimprovement，thetotalefectiveratewas82．4％．Bycontrast，14patientsincontrolgroupwitnessedsignificantrecoveryand12showedimprovement，thetotalefectiveratewas76．5％．Thetot

8、alefectiveratesofthetwogroupsshowednostatisticalsignificance(P>O．05)．Butthesignifi