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时间:2020-05-04
《健康查体人群非酒精性脂肪肝发病的相关危险因素分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·4714·现代生物医学进展www.shengwuylxue.comProgressinModernBiomedicineVoL14N024AUG2014doi:10.13241/j.cnki.pmb.2014.24.029健康查体人群非酒精性脂肪肝发病的相关危险因素分析冰杜凯音徐洪涛张宝和李静康怡胡晓东王吉孙洪良连士杰华伟王铁燕郭晓东(1海军总医院干部保健科北京100048;2北京同仁医院北京100730;3海军机关门诊部北京100841;4解放军第302医院北京100039)摘要目的:探讨非酒精性单纯性脂肪肝
2、以及由其演变的脂肪性肝炎各指标的差异,并分析非酒精性脂肪肝病(NonalcoholicFattyLiverDisease,NAFLD)的相关影响因素,为NAFLD防治提供依据。方法:入选病例分为正常组(A组,n=l89)、单纯性脂肪肝组(B组,n=162)、脂肪肝伴肝功能改变组(C组,n=23),分析其体检结果及生活方式等影响因素,应用单因素及Logistic回归分析进行统计学处理。结果:C组大多数各项指标均比B组有所升高,其中体质量指数(BMI)、丙氨酸转氨酶(ALT)、低密度脂蛋白胆固醇(LDL.C)、尿素氮
3、(BUN)、空腹胰岛素(Fins)、餐后2小时胰岛素(2hPins)差异有统计学意义(P<0.05)。在B组和c组中ALT、高密度脂蛋白胆固醇(HDL—C)、甘油三酯(TG)、Fins、2hPIns、腰臀比(wHR)与A组比较均有显著差异(P<0.05);男性NAFLD的发病率比女性高,差异有统计学意义(xZ=_6.86,P4、.39,P5、UndergoingPhysicalExamination木DUKai-yin1,XUHong-tao,ZHANGBao-h#,LI]1n~,KANGYi1,HUXiao—don~,WANGJilSUNHong-liang~,LIANShi-jie1,HUAWei1,WANGTie-yah3,GUOXiao-donga《lDepartmentofCadreHealthCal"GBeijing,10004&China;2BeijingTongrenHospital,Beijing,100730,China;3Dep6、artmentofOut-patient,NavyCadreCourtyard,Beijing,100841,China;4302HospitalofPLA,Beijing,10003~ChinaJABSTRACTObjective:Toinvestigatethediferencesofmarkersbetweennonalcoholicsimplefattyliver(NAFL)andnonalcoholicsteatohepatitis(NASH)inpeoplewhoweretakingthephysic7、alexamination,andtoanalyzetheriskfactorsofnonalcoholicfattyliverdisease(NAFLD)soastoprovideanevidenceforNAFLDtreatment.Methods:ThecaseswereclassifiedintogroupA(controlgroup,nl89),groupB(NAFL,n162)andgroupC(NASH,n=23).Thephysicalexaminationresultsandlifestylew8、ereanalyzed.TheunivariateanalysisandLogisticregressionanalysiswasapplied.Results:MostofthemakersingroupCwerehigherthanthatingroupB.BMI,ALT,LDL·C,BUN,Finsand2hPInsshowedsignificantdiferenc
4、.39,P5、UndergoingPhysicalExamination木DUKai-yin1,XUHong-tao,ZHANGBao-h#,LI]1n~,KANGYi1,HUXiao—don~,WANGJilSUNHong-liang~,LIANShi-jie1,HUAWei1,WANGTie-yah3,GUOXiao-donga《lDepartmentofCadreHealthCal"GBeijing,10004&China;2BeijingTongrenHospital,Beijing,100730,China;3Dep6、artmentofOut-patient,NavyCadreCourtyard,Beijing,100841,China;4302HospitalofPLA,Beijing,10003~ChinaJABSTRACTObjective:Toinvestigatethediferencesofmarkersbetweennonalcoholicsimplefattyliver(NAFL)andnonalcoholicsteatohepatitis(NASH)inpeoplewhoweretakingthephysic7、alexamination,andtoanalyzetheriskfactorsofnonalcoholicfattyliverdisease(NAFLD)soastoprovideanevidenceforNAFLDtreatment.Methods:ThecaseswereclassifiedintogroupA(controlgroup,nl89),groupB(NAFL,n162)andgroupC(NASH,n=23).Thephysicalexaminationresultsandlifestylew8、ereanalyzed.TheunivariateanalysisandLogisticregressionanalysiswasapplied.Results:MostofthemakersingroupCwerehigherthanthatingroupB.BMI,ALT,LDL·C,BUN,Finsand2hPInsshowedsignificantdiferenc
5、UndergoingPhysicalExamination木DUKai-yin1,XUHong-tao,ZHANGBao-h#,LI]1n~,KANGYi1,HUXiao—don~,WANGJilSUNHong-liang~,LIANShi-jie1,HUAWei1,WANGTie-yah3,GUOXiao-donga《lDepartmentofCadreHealthCal"GBeijing,10004&China;2BeijingTongrenHospital,Beijing,100730,China;3Dep
6、artmentofOut-patient,NavyCadreCourtyard,Beijing,100841,China;4302HospitalofPLA,Beijing,10003~ChinaJABSTRACTObjective:Toinvestigatethediferencesofmarkersbetweennonalcoholicsimplefattyliver(NAFL)andnonalcoholicsteatohepatitis(NASH)inpeoplewhoweretakingthephysic
7、alexamination,andtoanalyzetheriskfactorsofnonalcoholicfattyliverdisease(NAFLD)soastoprovideanevidenceforNAFLDtreatment.Methods:ThecaseswereclassifiedintogroupA(controlgroup,nl89),groupB(NAFL,n162)andgroupC(NASH,n=23).Thephysicalexaminationresultsandlifestylew
8、ereanalyzed.TheunivariateanalysisandLogisticregressionanalysiswasapplied.Results:MostofthemakersingroupCwerehigherthanthatingroupB.BMI,ALT,LDL·C,BUN,Finsand2hPInsshowedsignificantdiferenc
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