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ID:54924636
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时间:2020-05-04
《不同种类栓塞剂联合经皮肝穿刺注射无水酒精碘化油乳剂治疗中晚期肝癌的疗效评价(附58例分析)-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、口固⋯⋯论著不同种类栓塞剂联合经皮肝穿刺注射无水酒精碘化油乳剂治疗中晚期肝癌的疗效评价(附58例分析)石德强祁波许晓清山东省青岛市胶州中心医院放射科,山东青岛266300【摘要】目的探讨不同种类栓塞剂经肝动脉灌注化疗栓塞(TACE)经皮肝穿刺注射无水酒精碘化油乳剂联合治疗中晚期肝癌的疗效评价。方法采用不同栓塞剂结合化疗药物进行TACE单独治疗中晚期肝癌32例;TACE—PLE1T联合治疗26例。术后对比1年、2年、3年生存率并对其疗效进行评价。结果TACE组肿瘤血管消失有效率为31.2%,TACE—PLEIT组肿瘤
2、血管消失有效率为69.2%。所有治疗前AFP阳性HCC患者,治疗后均有不同程度的降低。TACE组1、2、3年生存率分别为75%、37.5%、15.6%,TACE—PLEIT组1、2、3年生存率分别为96.2%、84.6%、46.1%。结论采用不同栓塞剂化疗栓塞(TACE)联合PLEIT是治疗中晚期肝癌最有效方法,可以提高HCC患者的疗效及生存期。[关键词】栓塞剂;肝细胞癌;无水酒精;碘化油;疗效评价【中图分类号】R735.7【文献标识码】A【文章编号】1674—0742(2013)09(a卜0014-03Evalu
3、ationoftheEficacyofDiferentEmbolicAgentsCombinedwithPer.cutaneousEthanolandLipiodoInjectionintheTreatmentofAdvancedHepatocellularCarcinoma(ClinicalStudyof58Cases)SHIDeqiangQIBoXUXiaoqingDepartmentOfRadiology,JiaozhouCentralHospitalofQingdao,Qingdao,ShandongPro
4、vince,266300,China[Abstract]ObjectiveToevaluatetheefficacyoftranseatheterarterialchemoembolization(TACE)withdiferentembolieagentscombinedwithpercutaneousethanolandlipiodoinjectioninthetreatmentofadvancedhepatocellularcarcinoma(Hcc).Methods32casesofadvancedhepa
5、tocellularcarcinomaweretreatedwithTACEwithdiferentembolicagentsandchemotherapeuticdrugs;26casesweretreatedwithTACE—PLEITcombinedtreatment.Postoperativesurvivalratesof1year,2yearsand3yearsofthegroupswerecomparedandtheefficacieswereevaluated.ResultsTumorvesseldi
6、sappearedeficiencyofTACEgroupwas31.2%.whilethatoftheTACE—PLEITgroupwas69.2%.AFPlevelsofalltheHCCpatientswithpositiveAFPbeforetreatmentdecreasedwithdiferentdegreesafterthetreatment.1-yearsurvivalrate,2-yearsurvivalrateand3-yearsurvivalrateofTACEgroupwas75%,37.5
7、%and15.6%,respectively,whilethoseofTACE-PLEITgroupwas96.2%,84.6%and46.1%,respectively.ConclusionTACEwithdiferentembolicagentscombinedwithPLEITisaneffectivewayfortheadvancedhepatocellularcarcinoma,whichcanimprovethecurativeefectoftreatmentandsurvivaltimeofthepa
8、tientswithHCC.[Keywords]Embolicagent;Hepatocellularcarcinoma;Anhydrousalcohol;Lipiodo;Evaluationofcurativeefect肝细胞癌是临床常见恶性肿瘤之一,死亡率仅次于胃癌占1资料与方法第2位【1]。临床上首选的治疗方法是手术结合放化疗,然而,只有1.1一般资料
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