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时间:2020-05-02
《右美托咪定对心脏手术麻醉诱导期间血流动力学的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、心血管病防治知识2014年第4期l稚论著/社区人群防治始右美托咪定对心脏手术麻醉诱导期间血流动力学的影响张俊峰(云南省普洱市人民医院,云南普洱665000)【摘要】目的重点研究和探讨右美托咪定对心脏手术的麻醉效果以及麻醉诱导期间血流动力学的影响。方法利用回顾性分析的方法研究和比较对我院于2010年1月1日一2013年11月31日期间收治的l14例行心脏手术麻醉患者的临床资料进行回顾性对照分析。将患者随机分为2组,均给予常规静脉麻醉,观察组总计57例在常规静脉麻醉的基础上静脉注射右美托咪定;对照组总计57例在常规静脉麻醉的基
2、础上静脉注射与观察组等量的生理盐水。然后将2组数据结果进行分析,分析探讨两组患者麻醉效果以及麻醉诱导期间血流动力学的影响。结果通过对我院收治的ll4例行心脏手术麻醉患者的临床资料进行分析,两组患者在注药后5min时MAP值均明显下降,对照组下降幅度更大fP3、力恢复时问均好于对照组患者(p(0.05o结论右美托咪定对心脏手术患者具有很好的麻醉效果,并且能够平稳血流动力学相关指标,目前已经成为行心脏手术静脉麻醉患者的主要药物。值得临床借鉴和进一步推广。【关键词】右美托咪定;心脏手术;麻醉诱导期;血流动力学;静脉麻醉EfectofdexmedetomidineonhemodynamicsduringinductionofanesthesiaincardiacsurgeryZHANGJun-fengThePeopleHospitalof尸,er.ph,er665000,China)[4、Abstract]ObjectiveToinvestigatetheanestheticefectofdexmedetomidineincardiacsurgeryanditsefectonhemodynamicsduringinductionofanesthesia.MethodsAretrospectivecomparativeanalysiswasperformedontheclinicaldataof114patientswhounderwentanesthesiaincardiacsu~eryinourhospi5、talfromJanuary1,2010toNovember31,2013.Thesepatientswererandomlydividedintoobservationgroup(n=57)andcontrolgroup(n=57).Bothgroupsreceivedroutineintravenousanesthesia;inaddition,theobservationgroupwasintravenouslyinjectedwithdexmedetomidine,whilethecontrolgroupwasin6、travenouslyinjectedwithanequalvolumeofnormalsaline.Theobtaineddatawereanalyzedtocomp~etheanestheticefectandhemodynamicsduringinductionofanesthesiabetweenthetwogroups.ResultsAt5rainafterinjection,bot}lgroupshadsignificantlydecreasedmeanarterialpressurefMAP),butthec7、ontrolgrouphadasignificantlyhigherdecrease(尸<0.05).At10,15,and30rainafterinjection,theMAPdecreasednonsignifieantlycomp~edwiththebaselinevalue.At5minafterinjection,theheartrateofcontrolgroupincreasedsignificantlycomp~edwiththebaselinevaluefP8、cantdiferenceinbloodoxygensaturationbetweenthetwogroups.05).TheobservationgroupWassuperiortothecontrolgroupintermsofpostoperativepainSCOre,timetoawakeni
3、力恢复时问均好于对照组患者(p(0.05o结论右美托咪定对心脏手术患者具有很好的麻醉效果,并且能够平稳血流动力学相关指标,目前已经成为行心脏手术静脉麻醉患者的主要药物。值得临床借鉴和进一步推广。【关键词】右美托咪定;心脏手术;麻醉诱导期;血流动力学;静脉麻醉EfectofdexmedetomidineonhemodynamicsduringinductionofanesthesiaincardiacsurgeryZHANGJun-fengThePeopleHospitalof尸,er.ph,er665000,China)[
4、Abstract]ObjectiveToinvestigatetheanestheticefectofdexmedetomidineincardiacsurgeryanditsefectonhemodynamicsduringinductionofanesthesia.MethodsAretrospectivecomparativeanalysiswasperformedontheclinicaldataof114patientswhounderwentanesthesiaincardiacsu~eryinourhospi
5、talfromJanuary1,2010toNovember31,2013.Thesepatientswererandomlydividedintoobservationgroup(n=57)andcontrolgroup(n=57).Bothgroupsreceivedroutineintravenousanesthesia;inaddition,theobservationgroupwasintravenouslyinjectedwithdexmedetomidine,whilethecontrolgroupwasin
6、travenouslyinjectedwithanequalvolumeofnormalsaline.Theobtaineddatawereanalyzedtocomp~etheanestheticefectandhemodynamicsduringinductionofanesthesiabetweenthetwogroups.ResultsAt5rainafterinjection,bot}lgroupshadsignificantlydecreasedmeanarterialpressurefMAP),butthec
7、ontrolgrouphadasignificantlyhigherdecrease(尸<0.05).At10,15,and30rainafterinjection,theMAPdecreasednonsignifieantlycomp~edwiththebaselinevalue.At5minafterinjection,theheartrateofcontrolgroupincreasedsignificantlycomp~edwiththebaselinevaluefP8、cantdiferenceinbloodoxygensaturationbetweenthetwogroups.05).TheobservationgroupWassuperiortothecontrolgroupintermsofpostoperativepainSCOre,timetoawakeni
8、cantdiferenceinbloodoxygensaturationbetweenthetwogroups.05).TheobservationgroupWassuperiortothecontrolgroupintermsofpostoperativepainSCOre,timetoawakeni
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