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时间:2020-05-02
《不同年龄全麻非心脏手术病人术后认知功能障碍的比较.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、论著China&ForeignMedicalTreatment口—■■固■譬重_不同年龄全麻非心脏手术病人术后认知功能障碍的比较王铁全薛杰寇立华史洪淼刘禹含北京大兴区人民医院麻醉科.北京102600【摘要】目的探讨不同年龄组全麻非心脏手术病人术后认知功能障碍的发病情况及危险因素。方法择期手术病人90例,分3个年龄组,每组30例,groupl(青年组):20~44岁,gmup2(中年组):45—59岁,group3(老年fl~):60岁以上,分别于术前、术后24h内,术后1周对病人进行神经心理学问卷测试,包括简易精神状态评价量
2、表、数值广度试验(DSPT)}I~及逆向、数值符号试验(DSYT)、循环连线试验(TMT)、小故事记忆试验(SSMT)进行比较,每项试验与术前比较,大于2个标准差认为有意义,全部试验中大于2项有意义认定存在术后认知功能障碍。结果3组病人术后第一天pocd发病率分别是13.3%、23.3%、36.7%,术后一周发病率分别是6.7%、10.O%、13.3%,3者比较,差异无统计学意义(0.05),ASA为术后第一天的危险因素,而ASA分级与低氧血症为术后一周的危险因素。结论POCD的发生随年龄增加呈增多趋势。但差异无统计学意义,
3、ASA为术后第一天的危险因素,而ASA分级与低氧血症为术后一周的危险因素。【关键词】全麻;非心脏手术;术后认知功能障碍;不同年龄【中图分类号】R749【文献标识码】A[文章编号】1674—0742(2013)08(b)~0023—03ComparisonofPostoperativeCognitiveDysfunctionofDifferentAgesafterNoncardiacOperationwithGeneralAnesthesiaWANGT~quanXUEJieKOULihuaSHIHongmiaoLIUYuhan
4、DepartmentofAnesthesiology,PeoplesHospitalofBeijingDaxingDistrict,Beijing,102600,China【Abstract】0bjectiveTocomparetheincidenceofpostoperativecognitivedysfunction(POCD)ofdiferentagesafternoncardiacoperationwithgeneralanesthesiaandanalyzetherelativeriskfactorsoftheoc
5、currenceofPOCD.Methods90inpatientsweredi—videdinto3agegroups,30patientsineachgroup.Group1wasyounggroup,agedfrom20to44yearsold;group2wasmiddle-agedgroup,agedfrom45to59yearsoldandgroup3,theelderlygroup,aged60yearsorolder.Allthepatientswereaskedtofin·ishtheneuropsycho
6、logicalquestionnairetest,whichincludingMMSE,DSPT,DSYT,TMT,SSMT,preoperatively,24hafterthe0p—erationand1weekaftertheoperationrespectively.Theresultsoftestsaftertheoperationwerecomparedwiththosebeforeopera-tion,morethan2standarddeviationsweremeaningful,andifapatienth
7、admorethan2meaningfulitemsinallthetests,thenheorshewouldbediagnosedwithPOCD.ResultsTheincidenceofPOCDofthethreegroupswas13-3%.23-3%and36.7%respec—tively24haftertheoperation,andoneweekaftertheoperationtheincidencewasrespectively6.7%,10%and13_3%.Thedataofthethreegmup
8、swerecomparedandP>0.05;ASAwastheriskfactoroftheoccurrenceofPOCD24haftertheoperation,whileASAgradingandhypoxemiaweretheriskfactorsoftheoccurenceof
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