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时间:2020-04-25
《再障性和缺铁性贫血患者血清NO及NOS的临床价值评价-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、论著China&ForeignMedicalTreatment口—■誓固—譬幽再障性和缺铁性贫血患者血清NO及NOS的临床价值评价欧阳利华湖南省株洲市人民医院。湖南株洲412008【摘要】目的探讨一氧化氮(NO)以及一氧化氮合酶(NOS)对于再生障碍性贫IflI(AA)以及缺铁血性贫血(IDA)诊断及疗效判定的意义。方法收集2010年1月—2O13年9月期间,该院收治的AA患者24例作为AA组。并收集同期初诊IDA患者24例作为IDA组,选择同期健康体检者24例作为对照组,测定并对比分析3组的血清NO以及NOS水平。结果AA组以及IDA组的血清NO浓度以及NOS活性均显著
2、高于对照组(j)3、cAnemiaandIronDeficiencyAnemia0UYANGLihuaZhuzhouPeople"sHospitalofHunanProvince,Zhuzhou,HunanProvince,412008,China【Abstract]ObjectiveToinvestigatethesignificanceofnitricoxide(NO)andnitricoxidesynthase(NOS)forthediagnosisandca-rativeefectevaluationofaplastieanemia(AA)andirondeficiencyanemi4、a(IDA).Methods24casesofAApatientsadmittedinourhospitalfromJanuary,2010toSeptember,2013wereselectedastheAAgroup,and24casesofpatientsnewlydiagnosedwithIDApatientsduringthesameperiodwereselectedastheIDAgroup,and24casesofhealthypeopleunderwentphysicalexamina—tionduringthesameperiodwereselecte5、dasthecontrolgroup.TheserumNOandNOSlevelsofthesethreegroupsweremea—sured,comparedandanalyzed.ResultsThesertlmNOconcentrationandNOSactivityinAAgroupandIDAgroupweresignifi—candyhigherthanthoseofthecontrolgroupCP6、eenAAgroupandIDAgroup(P>0.o5);aftertreatment,theserumNOconcentrationandNOSactivityinAAgroupandIDAgroupreturnedtonormal,andcomparedwiththoseofthecontrolgroup,thediferenceWasnotstatisticallysignifcant(P>0.05).ConclusionNOandNOSmaybeinvolvedinthepathogenesisofAAandIDA,andwhichhavecertainsign7、ificanceinthediagnosisandcurativeefectjudgmentofAAandIDA.[Keywords]Irondeficiencyanemia;Aplasticanemia;Nitricoxidesynthase;Nitricoxide一氧化氮(NO)以及一氧化氮合酶(NOS)是由L一精氨酸在者的血清NO及NOS,旨在探讨NO及NOS以AA、IDA之间的催化作用下生成的脂溶性气体,两者的分子结构中均存在不配关系。现报道如下。对电子,属于自由基。目前已有大量研究证实,NO在调节免疫系1资料与方法统
3、cAnemiaandIronDeficiencyAnemia0UYANGLihuaZhuzhouPeople"sHospitalofHunanProvince,Zhuzhou,HunanProvince,412008,China【Abstract]ObjectiveToinvestigatethesignificanceofnitricoxide(NO)andnitricoxidesynthase(NOS)forthediagnosisandca-rativeefectevaluationofaplastieanemia(AA)andirondeficiencyanemi
4、a(IDA).Methods24casesofAApatientsadmittedinourhospitalfromJanuary,2010toSeptember,2013wereselectedastheAAgroup,and24casesofpatientsnewlydiagnosedwithIDApatientsduringthesameperiodwereselectedastheIDAgroup,and24casesofhealthypeopleunderwentphysicalexamina—tionduringthesameperiodwereselecte
5、dasthecontrolgroup.TheserumNOandNOSlevelsofthesethreegroupsweremea—sured,comparedandanalyzed.ResultsThesertlmNOconcentrationandNOSactivityinAAgroupandIDAgroupweresignifi—candyhigherthanthoseofthecontrolgroupCP6、eenAAgroupandIDAgroup(P>0.o5);aftertreatment,theserumNOconcentrationandNOSactivityinAAgroupandIDAgroupreturnedtonormal,andcomparedwiththoseofthecontrolgroup,thediferenceWasnotstatisticallysignifcant(P>0.05).ConclusionNOandNOSmaybeinvolvedinthepathogenesisofAAandIDA,andwhichhavecertainsign7、ificanceinthediagnosisandcurativeefectjudgmentofAAandIDA.[Keywords]Irondeficiencyanemia;Aplasticanemia;Nitricoxidesynthase;Nitricoxide一氧化氮(NO)以及一氧化氮合酶(NOS)是由L一精氨酸在者的血清NO及NOS,旨在探讨NO及NOS以AA、IDA之间的催化作用下生成的脂溶性气体,两者的分子结构中均存在不配关系。现报道如下。对电子,属于自由基。目前已有大量研究证实,NO在调节免疫系1资料与方法统
6、eenAAgroupandIDAgroup(P>0.o5);aftertreatment,theserumNOconcentrationandNOSactivityinAAgroupandIDAgroupreturnedtonormal,andcomparedwiththoseofthecontrolgroup,thediferenceWasnotstatisticallysignifcant(P>0.05).ConclusionNOandNOSmaybeinvolvedinthepathogenesisofAAandIDA,andwhichhavecertainsign
7、ificanceinthediagnosisandcurativeefectjudgmentofAAandIDA.[Keywords]Irondeficiencyanemia;Aplasticanemia;Nitricoxidesynthase;Nitricoxide一氧化氮(NO)以及一氧化氮合酶(NOS)是由L一精氨酸在者的血清NO及NOS,旨在探讨NO及NOS以AA、IDA之间的催化作用下生成的脂溶性气体,两者的分子结构中均存在不配关系。现报道如下。对电子,属于自由基。目前已有大量研究证实,NO在调节免疫系1资料与方法统
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