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时间:2020-04-23
《瑞芬太尼对重型颅脑损伤患者脑氧代谢及脑血流的影响-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·40·中国实用神经疾病杂志2014年4月第17卷第7期ChineseJournalofPracticalNervousDiseasesApr.2014,Vo1.17No.7I-7]陈克强,肖礼花,钟建新.依达拉奉治疗高血压脑出血的有效性[9]肖家平.依达拉奉对脑出血患者血清白介素一6和基质金属蛋和安全性研究[J].中国实用神经疾病杂志,2010,13(7):20—22.白酶一9水平的影响及疗效分析[J].中国当代医药,2010,17[8]龙霄翱,梁远生,陈兵.微创血肿清除术后高压氧联合依达拉(17)
2、:29—31.奉治疗高血压脑出血疗效观察[J].中华全科医学,2011,9(7):(收稿2013-09—23)1022—1024.瑞芬太尼对重型颅脑损伤患者脑氧代谢及脑血流的影响王言武湖北襄阳市铁路中心医院麻醉科襄阳441100【摘要】目的探讨瑞芬太尼对重型颅脑损伤患者脑氧代谢的影响。方法回顾性分析我院收治的64例重型颅脑损伤患者的临床资料,根据麻醉药物不同分为治疗组和对照组,对照组采用芬太尼麻醉,治疗组采用瑞芬太尼麻醉,比较2组患者麻醉前、麻醉后10min时脑氧代谢指标和血流动力学指标。结果麻醉前2
3、组患者的脑氧代谢指标和血流动力学指标比较均无显著性差异(P>O.05);麻醉后10min治疗组CERO显著高于对照组,CjvO、Da-jvO均显著低于对照组(P%0.05);治疗组Qmean、Wv显著高于对照组,DR显著低于对照组(P4、ctofremifentaniloncerebraloxygenmetabolismandcerebralbloodflowofpatientswithseverebraininjuryWangYanwuDepartmentofAnesthesiology,RailwayCentralHospitalofXiangyang,Xiangyang441i00,China[Abstract]ObjectiveToinvestigatetheeffectofremifentaniloncerebraloxyg5、enmetabolismandcerebralbloodflowofpatientswithseverebraininjury.MethodsRetrospectiveanalysisoftheclinicaldataofthe64caseswithsevereheadinjuryad—mittedtooLtrhospitalwasprocessed.Accordingtotheanestheticdrugs,64casesweredividedintotreatmentgroupandcontrol6、group,thecontrolgroupwastreatedwithfentanylforanesthesia,thetreatmentgroupwastreatedwithremifentanilforanes—thesia.Cerebraloxygenmetabolismandhemodynamieindexesofthetwogroupsbeforeanesthesiaandafteranesthesiafor10minwerecompared.ResultsBeforeanesthesia,7、brainoxygenmetabolismandhemodynamicparametersofthetwogroupswerenotsignificantlydifferent,P>0.05;10minafteranesthesia,CERO2ofthetreatmentgroupwassignificantlyhigherthanthatofthecontrolgroup,cjvO2,Da-jvO2aresignificantlylowerthanthatofthecontrolgroup,P%0.8、05;Qmean,Wvofthetreatmentgroupweresignificantlyhigherthanthoseofthecontrolgrohp;DRwassignificantlylowerthanthatofthecontrolgroup,P<0.05.ConclusionRemifentanilanesthesiaforpatientswithsevereheadinjurysurgerycanimprovecerebraloxyge
4、ctofremifentaniloncerebraloxygenmetabolismandcerebralbloodflowofpatientswithseverebraininjuryWangYanwuDepartmentofAnesthesiology,RailwayCentralHospitalofXiangyang,Xiangyang441i00,China[Abstract]ObjectiveToinvestigatetheeffectofremifentaniloncerebraloxyg
5、enmetabolismandcerebralbloodflowofpatientswithseverebraininjury.MethodsRetrospectiveanalysisoftheclinicaldataofthe64caseswithsevereheadinjuryad—mittedtooLtrhospitalwasprocessed.Accordingtotheanestheticdrugs,64casesweredividedintotreatmentgroupandcontrol
6、group,thecontrolgroupwastreatedwithfentanylforanesthesia,thetreatmentgroupwastreatedwithremifentanilforanes—thesia.Cerebraloxygenmetabolismandhemodynamieindexesofthetwogroupsbeforeanesthesiaandafteranesthesiafor10minwerecompared.ResultsBeforeanesthesia,
7、brainoxygenmetabolismandhemodynamicparametersofthetwogroupswerenotsignificantlydifferent,P>0.05;10minafteranesthesia,CERO2ofthetreatmentgroupwassignificantlyhigherthanthatofthecontrolgroup,cjvO2,Da-jvO2aresignificantlylowerthanthatofthecontrolgroup,P%0.
8、05;Qmean,Wvofthetreatmentgroupweresignificantlyhigherthanthoseofthecontrolgrohp;DRwassignificantlylowerthanthatofthecontrolgroup,P<0.05.ConclusionRemifentanilanesthesiaforpatientswithsevereheadinjurysurgerycanimprovecerebraloxyge
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