超声弹性成像组织弥散定量分析技术在评估慢性肝病严重程度的临床应用研究-论文.pdf

《超声弹性成像组织弥散定量分析技术在评估慢性肝病严重程度的临床应用研究-论文.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、盔刍三星鲞箍期』!!sQ堕ndinM⋯edSeotember2014，Vo1．16，No．9·585··IJ缶床研究·超声弹性成像组织弥散定量分析技术在评估慢性肝病严重程度的临床应用研究杨娜冯蕾孙琰陈坤夏要友摘要目的探讨超声实时弹性成像组织弥散定量分析技术对慢性肝病的诊断价值。方法正常组(21例)、肝纤维化组(57例)及肝硬化组(13例)三组患者均行超声实时弹性成像检查，并将所取得的12个组织弥散定量参数进行对照研究。结果l2个参数中除峰度(KuRT)、相关陛(c0RR)外，三组间各数据比较差异均有统计

2、学意义；除KURT外，其余参数与肝病严重程度之间有良好的相关性(P

3、％AREA与慢性肝病的严重程度相关性最高，对区分慢性肝病各阶段方面有较好的诊断价值。关键词超声检查；弹性成像；慢性肝病[中图法分类号]R657．31；R445．1[文献标识码]AApplicationstudyonseveritydegreeofchronicliverdiseaseusingultrasonicelastographyquantitativeanalysisrANGNa，FENGLei，SUNran，CHENKun，XIAYaoyouDepartmentofUltrasound，the

4、SecondAfiliatedHospitalofKunmingMedicalUniversity，Kunming650101，ChinaABSTRACTObjectiveToevaluatethediagnosticvalueofchronicliverdiseaseusingreal-timeelastographytissuedispersionquantitativeanalysissoftware．MethodsTwenty-onehealthyvolunteers，57patientswit

5、hliverfibrosisand13patientswithlivercirrhosiswereexaminedbyreal—timeelastography．Twelveparametersoftissuedispersionquantitativeanalysisobtainedfromthistestwerecomparedwithpathologicalstagesofliverbiopsies．ResultsThereweresignificantdiferencesin12paramete

6、rsexceptforKURTandCORRamongthegroups．TherewasagoodcorelationbetweenotherparametersandpathologicalstagesexceptforKURT(P<0．05)．Amongtheparameters，theMEAN，％AREAandLFindexhadthehighestrelatedcoeficientr=-0．634，0．620，0．619)．TheROCcurvewasmadeby％AREA，LFindexan

7、dMEAN．Distinguishedbetweennormalgroupandliverfibrosis+cirrhosisgroupanddistinguishedbetweennormal+liverfibrosisgroupandlivercirrhosisgroup，theareasundertheROCcurvewere0．830，0．910(％AREA)；0．813，0．936(LFindex)；O．832，0．928(MEAN)．ConclusionItishelpfultodistin

8、guishliverchangesamonghealthyvolunteers，patientswithliverfibrosisandpatientswithlivercirhosisusingreal—timeultrasoundelastography．TheMEAN，LFindexand％AREAhavegreatvalueondiagnosingchronicliverdiseasebecauseoftheirhighestcor