Th2的调节作用-论文.pdf

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1、论著Lunzhu《中外医学研究》第12卷第16期(总第240~])2014年6月贞芪扶正颗粒对肺肾阴虚型慢性阻塞性肺疾病稳定期患者Th1／]rh2的调节作用肖惠珍①陈仁山①邹敏①熊承文①张军①【摘要】目的：探讨贞芪扶正颗粒能否改善肺肾阴虚型慢性阻塞性肺疾病稳定期患者Thl／Th2的失衡状态。方法：选取笔者所在医院收治的肺肾阴虚型慢性阻塞性肺疾病稳定期患者65例，随机分为治疗组34例和对照组31例。两组患者均给予化痰、解痉、平喘治疗，治疗组加用贞芪扶正颗粒口服，疗程3个月。观察治疗前后两组患者肺功能、IL一10、TNF—d浓度及中医证侯积分变化。结果：治疗后，治疗

2、组FEV、FEv．％较对照组及治疗前均有明显改善，差异有统计学意义(P

3、tofZhenqiFuzhengGranuleonThl／Th2inLung—kidney—yinDeficiencyTypeofStableCOPDPatients／XIAOHui-zhen，CHENRen-shan，ZOUMin，etaL／／ChineseandForeignMedicalResearch，2014，12(16)：8-10【AbstractlObjective：ToobservewhetherZhenqiFuzhengGranulecouldimprovetheimbalancestateofTh1／Th2inlung—kidney—yind

4、eficiencytypeofstableCOPDpatients．Method：65lung—kidney-yindeficiencytypeofstableCOPDpatientswererandomlydividedintothetreatmentgroupof34patientsandthecontrolgroupof31patients．Twogroupsofpatientswere百venexpectorant，antispasmodic，antiasthmatherapy，whilethetreatmentgroupwasaddedwithZhen

5、qiFuzhengGranule，thetreatmentcoursewas3months．Beforeandaftertreatment，twogroupsofpatientswerecheckedwithpulmonaryfunction，concentration0fIL一10andTNF—，andscoreofTCMsyndrome．Result：Afterthetreatment，thenumericalvalueofFEVI％andFEVlinthetreatmentgroupwerehigherthanthatofthecontrolgroup，t

6、hediferenceswerestatisticallysignificantfP

7、eased，theincreasingdegreeinthetreatmentgroupwasmoreobviousthaninthecontrolgroup，thediferencewasstatisticallysignificantfP<0．o5)．TheimprovementofTCMsyndromesinthetreatmentgroupwasbetterthanthatinthecontrolgroup(P

8、Th2inlung-ki