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时间:2020-04-21
《^18F-FDGPET-CTSUVmax与非小细胞肺癌手术患者预后的关系-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、论著《癌症进展》2014年3月第12卷第2期0NCOLOGYPROGRESS.Mar2014.Vo1.12.No.2侣F—FDGPET—CTSUV与max非小细胞肺癌手术患者预后的关系△赵世俊吴宁郑容刘瑛张雯杰梁颖张瀚李小萌中国医学科学院北京协和医学院肿瘤医院影像诊断科,PET.CT中心,北京100021摘要:目的探讨F.FDGPET—CTSUV⋯与非小细胞肺癌(non-smallcelllungcancer,NSCLC)患者术后生存期的关系。方法回顾性分析167例行F—FDGPET.CT检查并接受手术治疗的NSCLC患者的临床及随访资料。采用Kaplan—Meier法及Log—ran
2、k检验进行单因素生存分析,多因素生存分析采用Cox比例风险模型。结果单因素生存分析显示:SUV⋯、性别、年龄、吸烟史、肿瘤部位、原发肿瘤大小、血清TM水平、组织学类型、分化程度及pTNM分期均是影响本组患者预后的因素(P3、术,发射型计算机;体层摄影术,x线计算机;18F脱氧葡萄糖;标准化摄取值中图分类号:R734.2文献标志码:Adoi:10.1I877/j.issn.1672-1535.2014.12.02.19PrognosticsignificanceofSUVmon墙F-FDGPET-CTinpatientswithsurgicallyresectednon-smallcelllungcancer△ZHAOShi-junWUNing’。拌ZHENGRongLIUYing。,ZHANGWen.jieLIANGYingZHANGHanLIXiao.mengDepartmentofDiagnostic4、Imaging,PET—CTcenter,CancerHospital,ChineseAcademyofMedicalSciences&PekingUnionMedicalCollege,Beijing100021,ChinaAbstract:ObjectiveThestudyfocusedontheroleofmaximumstandardizeduptakevalue(SUV⋯)onF—FDGPET—CTinpredictingtheoutcomeofpatientswithsurgicallytreatedNSCLC.MethodOnehundredsixty—sevenNSCL5、Cpatients(110malesand57females,meanage60.4years)wereenrolledinthisstudy.AllpatientsunderwentpreoperativeF—FDGPET—CTscanfollowedbycurativesurgery.TheSUV,gender,age,smokinghistory,tumorlocation,tumorsize,tumormarkerlevel,histologictype,differentiationgradeandpTNMstagewereanalyzedforassociationwith6、overallsurvival(OS),usingthelog—ranktestforunivariatesurvivalanalysisandtheCoxproportionalhazardsmodelformuhivari-基金项目:高等学校博士学科点专项科研基金(20101106110017);首都I床特色应用研究项目(Z131107002213015);北京希望马拉松专项基金(LC2010B34);国家重大仪器专项课题(201YQ1706710)通信作者(Correspondingauthor),e—mail:cjr.wuning@vip.163.COB《癌症进展》2014年37、月第l2卷第2期ateanalysis.ResultForunivariateanalysisofoverallsurvival(OS),theSUV⋯,gender,age,smokingstatus,tumorlocation,primarytumorsize,tumormarkerlevel,histologictype,differentiationgradeandpTNMstagewereallsignifi—cantlyassoci
3、术,发射型计算机;体层摄影术,x线计算机;18F脱氧葡萄糖;标准化摄取值中图分类号:R734.2文献标志码:Adoi:10.1I877/j.issn.1672-1535.2014.12.02.19PrognosticsignificanceofSUVmon墙F-FDGPET-CTinpatientswithsurgicallyresectednon-smallcelllungcancer△ZHAOShi-junWUNing’。拌ZHENGRongLIUYing。,ZHANGWen.jieLIANGYingZHANGHanLIXiao.mengDepartmentofDiagnostic
4、Imaging,PET—CTcenter,CancerHospital,ChineseAcademyofMedicalSciences&PekingUnionMedicalCollege,Beijing100021,ChinaAbstract:ObjectiveThestudyfocusedontheroleofmaximumstandardizeduptakevalue(SUV⋯)onF—FDGPET—CTinpredictingtheoutcomeofpatientswithsurgicallytreatedNSCLC.MethodOnehundredsixty—sevenNSCL
5、Cpatients(110malesand57females,meanage60.4years)wereenrolledinthisstudy.AllpatientsunderwentpreoperativeF—FDGPET—CTscanfollowedbycurativesurgery.TheSUV,gender,age,smokinghistory,tumorlocation,tumorsize,tumormarkerlevel,histologictype,differentiationgradeandpTNMstagewereanalyzedforassociationwith
6、overallsurvival(OS),usingthelog—ranktestforunivariatesurvivalanalysisandtheCoxproportionalhazardsmodelformuhivari-基金项目:高等学校博士学科点专项科研基金(20101106110017);首都I床特色应用研究项目(Z131107002213015);北京希望马拉松专项基金(LC2010B34);国家重大仪器专项课题(201YQ1706710)通信作者(Correspondingauthor),e—mail:cjr.wuning@vip.163.COB《癌症进展》2014年3
7、月第l2卷第2期ateanalysis.ResultForunivariateanalysisofoverallsurvival(OS),theSUV⋯,gender,age,smokingstatus,tumorlocation,primarytumorsize,tumormarkerlevel,histologictype,differentiationgradeandpTNMstagewereallsignifi—cantlyassoci
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