保肛术与Miles术治疗直肠癌的疗效对比.doc

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1、保肛术与Miles术治疗直肠癌的疗效对比保肛术与Miles术治疗直肠癌的疗效对比摘要目的：探讨临床治疗直肠癌的有效术式。方法：收治直肠癌患者73例，根据术式将上述患者分为研究组41例与对照组32例；研究组接受保肛术治疗，对照组接受Miles术治疗。治疗结束后对患者进行为期3年的随访。结果：①两组手术时间相比差异无统计学意义(P>0.05),研究组术屮出血量、术后肛门排气时间、术后留置导尿管时间、住院总时间显著低于对照组，两组比较弟异有统计学意义(P〈0・05)。②观察组术后Karnofsky功能状态评分显著高丁•

2、对照组，两组比较差异有统计学意义(P<0.05)o③两组术后局部复发率、远处转移率、1年生存率、3年生存率相比差异无统计学意义(P〉0・05)。结论：保肛术与Miles术治疗直肠癌的远期疗效相当，但是保肛术具有术后恢复快、生存质量高等优点，因此保肛术是临床治疗直肠癌的有效术式。关键词保肛术M订es术直肠癌AbstractObjective：Toexploretheeffectiveoperationforclinicaltreatmentofrectalcancer.Method：73casesofPatient

3、swithrectalcancerarecuredinourhospitalfromJanuary2006toDecember2009,Theabovepatientsaredividec!into41casesoftheresearchgroupand32casesofthecontrolgroup；Patientswiththeteamacceptanalsphincterpreservation,ThecontrolgrouppatientsaccepttheMilesoperation.Wewil1fol

4、low-upthemafterthetreatmentforthreeyears.Results：①Therewasnostatisticallysignificantdifferencetocomparewithtwogroupsofpatientswithoperationtime(P<0.05),amountofbleeding,Postoperativeanalexhausttime、Postoperativeurethralcathetertimeandthetotaltimeinhospitaiint

5、heresearchgrouparesignificantlylowerthanthecontrolgroupduringoperation,therewasstatisticallysignificantdifferencetocomparewithtwogroups(P<0.05)・②TheresearchgroupissignificantlyhigherthanthecontrolgrouponKarnofskyperformancestatusscoreafteroperation,therewasst

6、atisticallysignificantdifferencetocomparewithtwogroups(P<0.05).Tocomparetwogroupsofpatientswithpostoperativelocalrecurrenceanddistantmetastasisrate,survivalrate1year,3yearsurvivalrate,therewasnostatisticallysignificantdifference(P>0.05).Conclusion：analsphinct

7、erpreservationandtheMilesoperationhavethequitelong-termcurativeeffect,But,analsphincterpreservationhaveadvantagesoffastrecovery,highqualityoflife,therefore,analsphincterpreservationIseffectiveintheclinicaltreatmentofrectalcancersurgery.KeywordsAnalsphincterpr

8、eservation；Milesoperation；Rectalcancer直肠癌是指发生在乙状结肠直肠交界处与齿状线之间的恶性肿瘤。直肠癌是消化系统常见的恶性肿瘤之一，位于消化道恶性肿瘤第2位［1］。手术是治疗直肠癌最主要的主要方法，但直肠癌术式较多，不同术式的疗效不一。为探讨临床治疗直肠癌的有效术式，本研究对保肛术与M订es术治疗直肠癌的疗效进行了对比分析，现报告如下