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时间:2020-04-05
《保肛术与Miles术治疗直肠癌的疗效对比.doc》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、保肛术与Miles术治疗直肠癌的疗效对比保肛术与Miles术治疗直肠癌的疗效对比摘要目的:探讨临床治疗直肠癌的有效术式。方法:收治直肠癌患者73例,根据术式将上述患者分为研究组41例与对照组32例;研究组接受保肛术治疗,对照组接受Miles术治疗。治疗结束后对患者进行为期3年的随访。结果:①两组手术时间相比差异无统计学意义(P>0.05),研究组术屮出血量、术后肛门排气时间、术后留置导尿管时间、住院总时间显著低于对照组,两组比较弟异有统计学意义(P〈0・05)。②观察组术后Karnofsky功能状态评分显著高丁•
2、对照组,两组比较差异有统计学意义(P<0.05)o③两组术后局部复发率、远处转移率、1年生存率、3年生存率相比差异无统计学意义(P〉0・05)。结论:保肛术与Miles术治疗直肠癌的远期疗效相当,但是保肛术具有术后恢复快、生存质量高等优点,因此保肛术是临床治疗直肠癌的有效术式。关键词保肛术M订es术直肠癌AbstractObjective:Toexploretheeffectiveoperationforclinicaltreatmentofrectalcancer.Method:73casesofPatient
3、swithrectalcancerarecuredinourhospitalfromJanuary2006toDecember2009,Theabovepatientsaredividec!into41casesoftheresearchgroupand32casesofthecontrolgroup;Patientswiththeteamacceptanalsphincterpreservation,ThecontrolgrouppatientsaccepttheMilesoperation.Wewil1fol
4、low-upthemafterthetreatmentforthreeyears.Results:①Therewasnostatisticallysignificantdifferencetocomparewithtwogroupsofpatientswithoperationtime(P<0.05),amountofbleeding,Postoperativeanalexhausttime、Postoperativeurethralcathetertimeandthetotaltimeinhospitaiint
5、heresearchgrouparesignificantlylowerthanthecontrolgroupduringoperation,therewasstatisticallysignificantdifferencetocomparewithtwogroups(P<0.05)・②TheresearchgroupissignificantlyhigherthanthecontrolgrouponKarnofskyperformancestatusscoreafteroperation,therewasst
6、atisticallysignificantdifferencetocomparewithtwogroups(P<0.05).Tocomparetwogroupsofpatientswithpostoperativelocalrecurrenceanddistantmetastasisrate,survivalrate1year,3yearsurvivalrate,therewasnostatisticallysignificantdifference(P>0.05).Conclusion:analsphinct
7、erpreservationandtheMilesoperationhavethequitelong-termcurativeeffect,But,analsphincterpreservationhaveadvantagesoffastrecovery,highqualityoflife,therefore,analsphincterpreservationIseffectiveintheclinicaltreatmentofrectalcancersurgery.KeywordsAnalsphincterpr
8、eservation;Milesoperation;Rectalcancer直肠癌是指发生在乙状结肠直肠交界处与齿状线之间的恶性肿瘤。直肠癌是消化系统常见的恶性肿瘤之一,位于消化道恶性肿瘤第2位[1]。手术是治疗直肠癌最主要的主要方法,但直肠癌术式较多,不同术式的疗效不一。为探讨临床治疗直肠癌的有效术式,本研究对保肛术与M订es术治疗直肠癌的疗效进行了对比分析,现报告如下
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