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时间:2020-04-19
《介入取栓联合替罗非班治疗急性下肢动脉栓塞的临床疗效分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、IIi;I固c20。14N。O,。.0。8。。.,。。论著介入取栓联合替罗非班治疗急性下肢动脉栓塞的临床疗效分析萧剑彬林少芒张智辉李强艾文佳刘金铃广州医科大学附属第二医院血管外科,广东广州510260【摘要】目的探讨介入取栓联合替罗非班在治疗急性下肢动脉栓塞的临床疗效及安全性。方法随机选取该院于2011年4月一2012年3月收治的急性下肢动脉栓塞患者52例(76肢)随机分为两组,对照组26例行Fogarty导管取栓术,治疗组26例患者除给予介入取栓外,术前术后给予替罗非班预防血栓形成,根据治愈率、死亡率、术后
2、再栓率以及截肢率评价两组方法的疗效。结果两组患者均成功取除大部分栓子,无死亡病例;治疗组和对照组的治愈率、术后再栓率以及截肢率分别为92.1%(35/38)和78.9%(30/38)、7.9%(3/38)和21.0%(8/38)、2.6%(1/38)和13.2%(5/38),差异有投机学性意义(P<0.01)。未发生出血等不良反应。结论Fogarty导管取栓术联合替罗非班对治疗急性下肢动脉栓塞的临床疗效及安全性均较好,且提升了手术成功率,具有较强的临床应用价值,值得临床推广。【关键词】下肢动脉急性栓塞;Fog
3、arty导管取栓术;替罗非班;临床疗效【中图分类号】R543.5【文献标识码】A【文章编号】1674—0742(2014)03(b)一0036—03AnalysisoftheEficacyOfInterventi0nalThrombectomyCombinedwithTirofibanintheTreatmentofAcuteLowerExtremityArterialEmbolismXIA0JianbinLINShaomangZHANGZhihuiLIQiangAIWenjia,LIUJinlingDepa
4、rtmentofVascularSurgery,TheSecondAfiliatedHospitalofGuangzhouMedicalUniversity,Guangzhou,GuangdongProvince,510260,China【Abstract】ObjectiveToinvestigatetheclinicalefficacyandsafetyofinterventionalthrombectomycombinedwithtirofibaninthetreatmentofacutelowerext
5、remityarterialembolism.Methods52casesofpatients(76limbs)withacutelowerextremityarterialembolismadmittedinourhospitalfromApril,2011toMarch,2012wererandomlydividedintotreatmentgroup(n=26)andcontrolgroup(n=26).ThecontrolgroupwastreatedwithFogartycatheterembole
6、ctomy.Besidesinterventionalthrombectomy,thetreatmentgroupwasgiventirofibanpreoperativelyandpostoperativelyforpreventingtheformationofthrombus.Theclinicaleficacyofthetwogroupswasevaluatedbycurerate,mortality,postoperativeembolismrelapserateandamputationrate.
7、ResultsMostthrombiin62caseswereremoved,andnodeathcase.Thecurerate,postoperativeembolismrelapserateandamputationrateofthetreatmentgroupandthecontrolgroupwere92.1%(35/38)and78.9%(30/38),7.9%(3/38)and21.0%(8/38),2.6%(1/38)and13.2%(5/38),respectively,andthedife
8、rencesbetweenthetwogroupswerestatisticallysignificant(尸
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