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1、疑苯磺酸鈣治疗非增殖期糖尿病视网膜病变的临床观察作者：管永清，刘瑞单位：石家庄市，河北医科大学第四医院眼科【摘要】目的观察非增殖期糖尿病视网膜病变(DR)患者服用拜苯磺酸钙药物治疗前、后的眼底变化，评估其对DR的疗效。方法我院DR78例(146眼)，按其眼底病变程度分为早期和中期。将早、中期患者各分为2组:试验组和对照组。其中早期病变的试验组为A组(23例44眼),对照组为B31(18例35眼)；中期病变的试验组为C组(21例35眼),对照组为D31.(16例32眼)。试验组服用耗苯磺酸钙3个月。所有患者用药前后进行视力、眼压、散瞳眼底照相、眼底血管荧光造影，并进行对比分析。结果梵
2、苯磺酸钙治疗后，A纽较B纽•眼底改善者明显增多，有效率高(PV0.05);C纽较D纽•眼底改善者明显増多，有效率高(PV0.05);A纽较C组眼底改善者明显増多，有效率高(PV0.05)。结论梵苯磺酸钙对非増殖期DR具有改善和稳定病变的作用，対早期病变疗效更为显著。【关键词】糖尿病视网膜病变；2’5二梵苯磺酸钙；荧光素血管造影术ClinicalobservationofcalciumdobesilateinthetreatmentofnonproliferativediabeticretinopathyGUANYongqing,LIURui.DepartmentofOp
3、hthidmology,TheFourthHospitalofHebeiMedicalUniversity,Shijiazhuang050011,China【Abstract］ObjectiveToobservethetherapeuticeffectofcalciumdobesilateonnonproliferativediabeticretinopathy(DR).Methods78diabeticpatients(146eyes)wereselected.Patientsweredividedintoexperimentalgroupandcontrolgroup.Nona
4、geexperimentalgroupwasnamedgroupA(23cases,44eyes),nonagecontrolgroupwasnamedgroupB(18cases,35eyes),metaphaseexperimentalgroupwasnamedgroupC(21cases,35eyes),andmetaphasecontrolgroupwasnamedgroupD(16cases,32eyes)・ThepatientsinexperimentalgroupAandgroupCtookdomesticcalciumdobesilatefor12weeks.Thr
5、eemonthsbeforeandaftertreatment,thepatients’vision,intraocularpressure,theconditionofretina,FFAwereobservedandcompared.ResultsAftertreatmentthenumberofpatientswithimprovementofeyegroundingroupAwassignificantlymorethanthatingroupB,sowastheeftectiverate(P&l{;0.05)・Thenumberofpatientswithim
6、provementofeyegroundingroupCwassignificantlymorethanthatingroupD,sowastheeffectiverate(P<0.05).ThenumberofpatientswithimprovementofeyegroundingroupAwassignificantlymorethanthatingroupC,sowastheeffectiverate(P&l(;0・05).ConclusionCalciumdobesilateiseffectiveintreatingnonproliferativeDR,whichi
7、smoreeffectiveforearlypathologicalchanges.【Keywords］diabeticretinopathy；calciumdobesilate；FFA糖尿病视网膜病变(DR)是主耍的致盲眼病之一，在中年人群的失明患者中DR跃居首位，越来越多的证据衣明DR与视网膜微血管病变及炎性反应密切相关［1］。过去人们曾用一般的血管扩张药、维生素及英他药物进行支持疗法，但其疗效不确切［2,3］。本文对确诊为非增殖期DRW者服用拜苯磺酸钙治疗，观察
