[精品]美托洛尔联合通心络胶囊治疗冠心病心绞痛的临床观察.doc

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1、美托洛尔联合通心络胶囊治疗冠心病心绞痛的临床观察美托洛尔联合通心络胶囊治疗冠心病心绞痛的临床观察［摘耍］目的探讨美托洛尔联合通心络胶囊治疗冠心病心绞痛的效果。方法将68例冠心病心绞痛患者，采用随机数字表法分为观察组(联合治疗组)及对照组(美托洛尔组)。入院后所有患者均给予常规基础治疗，在常规治疗的基础上，对照组患者给予美托洛尔，观察组除美托洛尔外加用通心络胶囊。对比观察两组患者的临床疗效、心电图改变、24h动态心电图变化。结果观察组患者的临床总有效率为88.24%,对照组为47.06%,两组差异有统计学意义(x2=13.170,P二0.000)

2、。观察组患者心电图改变的总有效率为94.12%,对照组为52.94%,两组差异有统计学意义(x2二14.809,P=0.000)o观察组患者的动态心电图发作性ST-T改善情况与对照组相比更为显著(P〈0.05)。结论美托洛尔联合通心络胶囊治疗冠心病心绞痛，对患者症状的改善效果显著，效果可靠，值得推广。［关键词］冠心病心绞痛；通心络胶囊；美托洛尔；临床疗效［中图分类号］R542.2［文献标识码］A［文章编号］1674-4721(2014)09(且)-0087-03Clinicalobservationofmetoprololcombinedwit

3、hTongxinluocapsuleinthetreatmentofanginapectorisofcoronaryheartdiseasesXTAOZhi-jieDepartmentofVasculocardiology,ShangraoPeople'sHospitaiofJiangxiProvince,Shangrao334100,China［Abstract］ObjectiveToexplorethecurativeeffectsofmetoprololcombinedwithTongxinluocapsuleinthetreatment

4、ofanginapectorisofcoronaryheartdiseases・Methods68patientswithanginapectorisofcoronaryheartdiseaseswereal1ocatedtoanobservationgroup(combinedtreatmentgroup)andacontrolgroup(metoprololgroup)basedonarandomnumbertable・Patientsweregivenregulartreatmentafteradmission.Onthebasisoft

5、heregulartreatment,thecontrolgroupwasgivenmetoprolol,andtheobservationgroupwasfurthergivenTongxinluocapsule.Clinicalefficacy,changesofelectrocardiogramandchangesof24-hourdynamicelectrocardiogrambetweenthetwogroupswerecomparedandobserved・ResultsTheclinicaltotaleffectiveratewa

6、s88.24%intheobservationgroupand47.06%inthecontrolgroupandthedifferencewasstatisticallysignificant(x2=13.170,P二0.000).Thetotaleffectiverateofchangesofelectrocardiogramwas94.12%intheobservationgroupand52.94%inthecontrolgroup,andthedifferencewasstatisticallysignificant(x2二14.80

7、9,P二0.000)・ImprovementofparoxysmalST~Tofdynamicelectrocardiogramintheobservationgroupwasmoresignificantthanthatinthecontrolgroup(P<0.05)・ConclusionMetoprololcombinedwithTongxinluocapsuleinthetreatmentofanginapectorisofcoronaryheartdiseaseshasasignificanteffectofalleviatingpa

8、tients'symptomsanditscurativeeffectisreliable,whichisworthyofclinicalpromot