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时间:2017-12-07
《650例前葡萄膜炎临床分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、中华眼视光学与视觉科学杂志2013年l2月第15卷第12期ChinJOptomOphthalmolVisSci,December2013,Vo1.15,No.12.747·临床研究·650例前葡萄膜炎临床分析陆晓雅王毓琴郑美琴徐一楼永良【摘要】目的探讨前葡萄膜炎的病因、类型、临床特点及预后。方法回顾性病例研究。分析2006年12月至2012年7月就诊于我院葡萄膜炎专科的650例前葡萄膜炎患者(856眼)的临床资料,根据病史、临床表现、合并全身性疾病、辅助检查及实验室检查等,对前葡萄膜炎的病因、临床特点、治疗效果及预后进行探讨。结果650例前葡萄膜炎患者(856眼)中单眼发
2、病444例,双眼发病206例,男394例,女256例,男女比例为1.5:1;平均发病年龄(39.0+15.0)岁,2O一5O岁之间的青壮年患者占总病例的71.4%。急性期689眼,慢性期167眼。按病因主要分为特发性前葡萄膜炎(243例,37.4%),不伴发全身关节病变的HLA—B27相关性前葡萄膜炎(123例,18.9%),强直性脊柱炎(105例,16.2%),Fuchs综合征(74例,11-4%)和病毒感染(44例,6.8%)。各种并发症发生率为39.5%,主要为并发性白内障(41.1%)和继发性青光眼(35.1%)。治疗后视力≥0.5者占75.4%,0.05~者占2
3、O.3%,<0.05者占4-3%。结论前葡萄膜炎发病率高,病因复杂多样,易复发,如治疗不当将产生严重并发症。因此应对前葡萄膜炎患者进行详细、系统的检查,积极查因,从而指导临床治疗及预后。【关键词】葡萄膜炎,前;病因;治疗结果;预后Clinicalanalysisof650patients、订manterioruveitisLUXiao—ya,WANGYu—qin,ZHENGMei—qin,XUYi,LOUYong—liang.SchoolofLaboratoryMedical,WenzhouMedicalUniversity,Wenzhou325035,ChinaCorr
4、espondingauthor:LOUYong-liang,Email:lyl@wzmc.edu.en【Abstract】ObjectiveToinvestigatetheprevalenceofanterioruveitisandtoassesstheetiology,classification,clinicalfeatures,treatmentoutcomesandprognosisofuveitis.MethodsSixhundredfiftypatients(206patientswerebilatera1)withanterioruveitisreferre
5、dtotheEyeHospitalofWenzhouMedicalUniversityduringtheperiodofDecember2006toJuly2012wereretrospectivelyanalyzed.Theetiology.clinicalcharacteristics。treatmentoutcomesandprognosisbasedonthecasehistory,clinicalmanifestation,systemicdiseases,auxiliaryexaminationandlaboratoryexaminationwereasses
6、sed.Resultsn1eaverageageatdiseaseonset(394malesand256females)was39.0_+15.0years.Therewere689eyeswithacuteanterioruveitisand167eyeswithchronicanterioruveitis.Themostcommontypewasidiopathicuveitis(243cases,37.4%),anditwasfollowedindescendingorderbyHLA—B27associateduveitisthatwasnotaccompani
7、edbysystemicarthriticdisease(123cases,18.9%),ankylosingspondylitis(105cases,16.2%),Fuchssyndrome(74cases,11.4%)andvirusinfection(44cases,6.8%).Therateofcomplicationswas39.5%.Therateofmildvisualimpairment(0.05~)was20.3%andtherateofblindness(1essthan0.05)was4.3%.Concl
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