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1、2006年1月护理学报January,200660第13卷第1期JournalofNursing(China)Vol.13No.1【药械护理】硝酸甘油舌下滴服对麻醉苏醒期高血压的影响许菊霞,周春莲,王惠琴(浙江省台州医院麻醉科,浙江台州317000)[摘要]目的比较硝酸甘油舌下滴服与滴鼻对苏醒期高血压的降压效果及舒适度。方法硝酸甘油5mg用生理盐水稀释至10ml备用。100例全麻术后高血压病人分为舌下滴服组、滴鼻组各50例。舌下滴服组示其舌头上翘,不能上翘者用消毒棉签轻轻挑起舌头后往舌下滴入配制好的硝酸甘油0.5ml。滴
2、鼻组用生理盐水棉签清洁两侧鼻腔后滴入硝酸甘油0.5ml。给药后1、3、5、10、15min记录血压、心率。观察15min,无效者则予第2次给药。结果两种方法均可使苏醒期血压下降至基础水平,1～3min起效,5min达到最大效应,维持15～30min。两组血压下降速度及下降水平无显著性差异(P>0.05)。两组用药次数无显著性差异(P>0.05)。滴鼻组有17例诉鼻腔刺激不适,9例有刺激味、恶心感;而舌下滴服组仅11例诉有刺激味,2例有恶心感。结论硝酸甘油舌下滴服与硝酸甘油滴鼻相比,在苏醒期高血压病人中同样具有操作简便、快
3、速、安全、有效等优点,舌下滴服较滴鼻的方法更能减轻病人痛苦。[关键词]硝酸甘油;麻醉苏醒期;高血压;舌下滴服;滴鼻[中图分类号]R614.2[文献标识码]A[文章编号]1008-9969(2006)01-0060-02TheInfluenceofDroppingNitroglycerinUnderTongueonHypertensionDuringPostoperativeAnestheticPeriodXUJu-xia,ZHOUChun-lian,WANGHui-qin(Dept.ofAnesthesia,Zhejia
4、ngTaizhouHospital,Taizhou317000,China)Abstract:ObjectiveTocomparethelowingpressureeffectandcomfortdegreeofdroppingNitroglycerinundertongueandnosedropping.MethodsFivemgNitroglycerinwasdilutedinto10mlwithsalinesolutiononstandby.Onehundredpatientsaftergeneralanesthe
5、ticweredividedintodroppingunderthetonguegroupof50patientsandnosedroppinggroupof50patients.Inthedroppingunderthetonguegroup,patientsweregiven0.5mlpreparedNitroglycerinunderthetongue,whileinthenosedroppinggroup,patientsweregiven0.5mlNitroglycerinbynosedroppingafter
6、cleaningnasalcavitybysalinesolutionandtampon.Thebloodpressureandheartratewererecordedat1min,3min,10minand15min.Ifitwasfoundineffectiveafter15minobservation,patientsweregivenmedicineagain.ResultsBothmethodscouldreducethehypertensiontonormallevel,theyreachedeffecti
7、veat1～3min,reachedmaximumat5minandmaintainedfor15～30min.Therewasnosignificantdifferencesinspeedofloweringhypertensionanddegreeofloweringhypertensionbetweentwogroups(P>0.05).Innosedroppinggroup,17feltdiscomfortbecauseofstimulationinnasalcavityand9feltsick,whileind
8、roppingunderthetonguegroup,11feltstimulatedand2feltsick.ConclusionForpatientsduringpostoperativeanestheticperiod,droppingNitroglycerinunderthetonguehassuchadva
