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时间:2017-12-07
《不同剂量地佐辛对瑞芬太尼静脉全麻术后苏醒期的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、HainanMedJ,Dec.2013,Voi.24,No.23海南医学2013年12月第24卷第23期doi:lO.3969/j.issn.1003—6350.2013.23.1446·论著·不同剂量地佐辛对瑞芬太尼静脉全麻术后苏醒期的影响罗小玲,欧阳伟子,赵丽(深圳市第七人民医院麻醉科,广东深圳518081)【摘要】目的研究不同剂量地佐辛对腹腔镜手术患者瑞芬太尼静脉全麻术后苏醒期的影响。方法选择100例腹腔镜手术患者,按随机数字表法分为实验组四组(T1组、T2组、T3组、T4组)和对照组(c组),每组20例。行双盲试验。在麻醉深度监测下行麻醉诱导及维持,维持药物为丙泊酚+瑞芬太
2、尼,术毕前15min,T1组、T2组、T3组、T4组分别静注地佐辛80~teCkg、60~tg/kg、40~g/kg、20~tg/kg,C组静注生理盐水1Oml,观察患者睁眼时间、呼吸恢复时间、拔管时间、疼痛视觉模拟评分(VAS)、恶心呕吐及躁动不良反应。结果T1组、T2组的睁眼时间、呼吸恢复时间、拔管时间明显较T3组、T4组和C组延长(P3、镜;苏醒期【中图分类号】R614.2【文献标识码】A【文章编号】1003---6350(2013)23—3479__o2Efectsofdezocineofdiferentdosesonremifentanilintravenousgeneralanesthesiapostoperativerevivalperiodunderthedepthofanesthesiamonitoring.LUOXiao-ling,OUYANGWei-zi,ZHAOLi.DepartmentofAnesthesiology,theSeventhPeopleHospitalofShenzhen,Shen4、zhen518081,Guangdong,CHINA【Abstract】ObjectiveToresearchtheefectsofdezocineofdiferentdosesonremifentanilintravenousgen—eralanesthesiapostoperativerevivalperiodunderthedepthofanesthesiamonitoring.MethodsAtotalof100lapa—roscopicsurgerypatientswereselectedanddividedinto4experimentalgroups(T1,T2,T35、,T4)andcontrolgroup(groupC1randomly,、m20casesineachgroup.Administerinductionandmaintenanceofanesthesiawereperformedbyusingremifentanilandpropofolunderthedepthofanesthesiamonitoring.Tenminutesbeforetheendofsurgery,in—travenousdezocinetothegroupTintheunitsof8O!.tg/kg,60~tg&g,40~tg/kg,20ug/kgresp6、ectively,10mlofsalinetogroupC.Recoverytimeofspontaneousbreathing,eyeopeningtime,extubationtime,alert/sedationscore(OAA/S),vi-sualanaloguescale(VAS)andadversereactionsofnausea,vomitinganddysphasiawereobserved.ResultsThere.coverytimeofspontaneousbreathing,eyeopeningtimeandextubationtimeingroupT17、andT2werelongerthanthoseingroupT3,T4andCsignificantly(P<0.05),butOAA/Swaslower(P<0.05).TheVASanddysphoriaincidenceingroupT4andCweresignificantlyhigherthanthoseinothergroups.ConclusionAppropriatedoseofdezocineCanef-fectivelypreventpainan
3、镜;苏醒期【中图分类号】R614.2【文献标识码】A【文章编号】1003---6350(2013)23—3479__o2Efectsofdezocineofdiferentdosesonremifentanilintravenousgeneralanesthesiapostoperativerevivalperiodunderthedepthofanesthesiamonitoring.LUOXiao-ling,OUYANGWei-zi,ZHAOLi.DepartmentofAnesthesiology,theSeventhPeopleHospitalofShenzhen,Shen
4、zhen518081,Guangdong,CHINA【Abstract】ObjectiveToresearchtheefectsofdezocineofdiferentdosesonremifentanilintravenousgen—eralanesthesiapostoperativerevivalperiodunderthedepthofanesthesiamonitoring.MethodsAtotalof100lapa—roscopicsurgerypatientswereselectedanddividedinto4experimentalgroups(T1,T2,T3
5、,T4)andcontrolgroup(groupC1randomly,、m20casesineachgroup.Administerinductionandmaintenanceofanesthesiawereperformedbyusingremifentanilandpropofolunderthedepthofanesthesiamonitoring.Tenminutesbeforetheendofsurgery,in—travenousdezocinetothegroupTintheunitsof8O!.tg/kg,60~tg&g,40~tg/kg,20ug/kgresp
6、ectively,10mlofsalinetogroupC.Recoverytimeofspontaneousbreathing,eyeopeningtime,extubationtime,alert/sedationscore(OAA/S),vi-sualanaloguescale(VAS)andadversereactionsofnausea,vomitinganddysphasiawereobserved.ResultsThere.coverytimeofspontaneousbreathing,eyeopeningtimeandextubationtimeingroupT1
7、andT2werelongerthanthoseingroupT3,T4andCsignificantly(P<0.05),butOAA/Swaslower(P<0.05).TheVASanddysphoriaincidenceingroupT4andCweresignificantlyhigherthanthoseinothergroups.ConclusionAppropriatedoseofdezocineCanef-fectivelypreventpainan
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