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1、中国中西医结合外科杂志2012年2月第18卷第1期27究[J].中国中西医结合外科杂志,2005,11(2):143-145.ingisolatedmousepancreaticacinarcells[J].JCellMolMed,[8]OhGS,PaeHO,LeeBS,etal.Hydrogensulfideinhibitsnitricox⁃2007,11(2):315-326.ideproductionandNF-кBviahemeoxygenase-1expressionin[11]ZhangH,ZhiL,MoochhalaSM,etal.Endog
2、enoushydrogensul⁃RAW264.7macrophagesstimulatedwithlipopolysaccharide[J].fideregulatesleukocytetraffickingincecalligationandpunc⁃FreeRadicBiolMed,2006,41(1):106-119.ture-inducedsepsis[J].JLeukocBiol,2007,82(10):894-905.[9]陈文亮,王选,韩曙.急性胰腺炎患者核因κB激活的检测[J].中(收稿:2011-06-06修回:2011-11-20)华
3、急诊医学杂,2005,14(7):579-581.(责任编辑瞿全)[10]TamizhselviR,MoorePK,BhatiaM.Hydrogensulfideactsasamediatorofinflammationinacutepancreatitis:invitrostudiesus⁃桥本甲状腺炎治疗及预后分析杨绪亮,刘彤摘要目的:探讨桥本甲状腺炎的临床诊断、治疗方法及其预后。方法:106例桥本甲状腺炎患者中,内科治疗40例,经甲状腺自身抗体检测或细针穿刺细胞学检查确诊,口服甲状腺素片治疗。手术治疗66例。随访时间0.5~6年,中位时间3年。结果:
4、内科治疗组新增甲状腺功能下降18例,外科治疗组新增甲状腺功能下降15例。结论:对于桥本甲状腺炎患者,严格遵守手术指征,对有气管压迫症状和无法排除合并恶性结节的患者选择适当手术方式,术后规律服药及监测甲状腺功能变化,可取得良好疗效。关键词:桥本甲状腺炎;甲状腺功能低下;治疗中图分类号:R653文献标识码:A文章编号:1007-6948(2012)01-0027-03doi:10.3969/j.issn.1007-6948.2012.01.008TherapeuticandPrognosticAnalysisofHashimoto'sThyroiditisYA
5、NGXu-liang,LIUTongDepartmentofGeneralSurgery,TianjinMedicalUniversity,AffiliatedGeneralHospital,Tianjin(300052),ChinaAbstractObjective:ToanalyzetheclinicalfeaturesandtreatmentandprognosisofHashimoto'sthyroid⁃itis(HT)MethodsClinicaldataof106casesofHTwerereviewed.Fortypatientsweretr
6、eatedwithEuthyrox,afterthetestofthyroidautoantibodiesorthetestbyfineneedleaspirationcytology.Surgicaltreatmentwasgivenin66patients.Allcaseswerefollowed-upfrom0.5to6yearswithamediantimeof3yearsResultInthegroupwithsurgicaltreatment,decreasedthyriodfunctionwasseenin15cases,ascompared
7、with18casesinthemedicaltreatmentgroup.ConclusionForpatientswithHT,surgicalapproachshouldbegivenstrictlyaccordingtosurgicalindications,suchascompressionsymptomsofthetracheaandundeniablenoddles.Postop⁃erativelong-termEuthyroxtreatmentandthemonitoringofthethyroidtestcouldachieveclini
8、calbenefit.Keywords:Hashimoto'sth