资源描述：
《针灸对原发性骨质疏松症影响的实验和临床研究.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、针灸对原发性骨质疏松症影响的实验和临床研究中国骨伤2000年第9期第13卷实验研究作者：刘献祥吴明霞吴炳煌章志安钱松涛李俐单位：刘献祥吴炳煌章志安钱松涛(福建中医学院，福建福州350003)：吴明霞李俐(福建省第二人民医院，福建福州)关键词：骨质疏松；骨密度；针刺疗法摘要：目的探讨针刺和艾灸治疗原发性骨质疏松症的疗效。方法动物实验采用12月龄雌性大鼠65只,随机分为正常对照组、手术对照组、模型纽.、雌二醇组、针刺纽.和艾灸纽采用摘除双侧卵巢法建立骨质疏松症的模型，造模3个月后治疗3个月，进行骨代谢生化指标、性激素水平、骨小梁等观测针刺和艾灸的
2、疗效。临床研究选择骨质疏松女性患者30例,随机分为针刺组和艾灸组各15例,治疗前和治疗3个月检查腰椎骨密度。结果经针刺、艾灸或雌二醇治疗后，S-AKP、U-Ca/Cr、U-HOP/Cr较模型组分别有所下降；S・E2、S-BGP较模型纽升高(p<0.05〜0.01)；骨小梁与髓腔的宽度比值，针刺、艾灸和雌二醇较模型组接近止常。30例骨质疏松患者骨密度治疗前和治疗后，针刺和艾灸组分别提高1.95%和2.43%。结论针刺、艾灸和雌二醇三者的作用无明显差异，针灸是防治骨质疏松症的有效方法之一。Experimentalandclinicalstudie
3、sofeffectsofacupunctureandmoxibustiononprimaryosteoporosis1IUXian-sciang,WUMing-Ma,WUBing-huang(FujianCollegeofTCMFujianFuzhou,350003)Abstract:ObjectiveToexploreexperimentalandclinicalresultsofacupunctureandmoxibustionforthetreatmentofprimaryosteoporosis・Methods65femaleS・D.
4、ratsaged12monthswererandomlydividedinto6groups:normalcontrolgroup,sham-cperatedgroup,modelsgroup,estradiolgroup,acupuncturegroup,moxibustiongroup.Osteoporosismodelswereproducedbybilateralovariectomy.Thetreatmentwascarriedoutinmodelsof3monthsandthetreatmentperiodlastedfor3mo
5、nths.Theeftectofacupunctureandmoxibustionwasdeterminedbythemeasurementofthebiochemicalindexesofbonemetabolism,thelevelofsexhormoneandbonemorphometry.Intheclinicaltests,30femalecasesofosteoporosiswererandomlydividedintotwogroups:acupuncturegroupandmoxibustiongroup.Bonedensit
6、yoflumbarvertebralwasdeterminedat3monthsbeforetreatmentandaftertreatment.ResultsAfterthetreatment,serum-AKP,Urine-Ca/Cr,UrineHOP/Crintheestradiolgroup,acupuncturegroupandmoxibustiongroupweresignificantlylower(haninthemodelgroup;serumestradiol(E2),BGPintheestradiolgroup,acup
7、uncturegroupandmoxibustiongroupweresignificantlyhigherthanthoseinthemodelgroup(p<0.05^0.01);thewidthratioofbonetrabeculatomarrowcavityintheestradiolgroup,acupuncturegroupandmoxibustiongroupwasclosetonormalstandardthanthatinthemodelgroup.Beforeandaltertreatment,thebonedensit
8、yof30casesintheacupuncturegroupandmoxibustiongroupraised1.95%and2.43%respectively.
