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1、RESEARCHHIGHLIGHTSNatureReviewsMicrobiology
2、AOP,publishedonline11March2013;doi:10.1038/nrmicro2998InthenewsNOVELCORONAVIRUSSPREADSWiththeidentificationofafamilyclusterofnovelcoronavirus(NCoV)infectionsintheUKandasinglenewcaseinSaudiArabiainFebruary2013,thenumberof
3、confirmedNCoVinfectionshasrisento13,sevenofwhichwerefatal(WHO,21Feb2013).TheUKclusterappearstohaveoriginatedfromamanwhorecentlytravelledtoSaudiArabia,whereNCoVwasfirstisolatedinSeptember2012.Aftertwooftheman’sfamilymembersalsofellill,JohnWatson,theheadoftheUK’sHea
4、lthProtectionAgency,saidthatsuchacluster“suggeststhatperson-to-persontransmissionoccurred”butgavenoreasonforincreasedalarm,asindicatedbyanunchangedriskassessmentfromtheWHO(Reuters,13Feb2013).TheabilityofNCoVtospreadbetweenhumanswaspreviouslyunclear,althoughan11-pe
5、rsonclusterofpneumoniainaJordanianhospitalinApril2012hintedthatitwaspossible.NCoVwasconfirmedinthetwofatalcases,andtheninenon-fatalcaseswereprobable,butunconfirmed,NCoVinfections.WHOspokesmanGregoryHartlsaid,“EvenifthecasesinJordanwerehuman-to-humanspread—andwedon
6、’tknowthat—itwasn’tsustained.”(NPR,30Nov2012.)VolkerThiel,leadauthorofoneofthefirstNCoVstudies,saidhisresearchshowedthatthevirus“wasjustaswelladaptedtoinfectingthehumanrespiratorytractasothercoronaviruseslikeSARSandthecommoncoldviruses”.Thielpointedoutthatthefutur
7、eofthevirusisuncertain,buthereiteratedthesentimentsoftheWHObystatingthat“Sofaritlookslikethevirusiswellcontained,sointhatsenseIdon’tseeanyreasonforincreasedfear”(Reuters,19Feb2013).ProfessorIanJones,avirologistattheUniversityofReading,UK,saidthat“Althoughitissever
8、e,it’snotdoinganythingworsethansomeotherrespiratoryinfections,it’sjustanewone.”(BBCNews,13Feb2013.)UrsulaHoferNATUREREVIEWS
9、MICROBIOLOGYVOLUME11
10、APRIL2013
11、1©2013MacmillanPublishersLimited.Allrightsreserved
