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1、药物治疗对妇科术后缺血性脑血管病的影响•妇产医学论文药物治疗对妇科术后缺血性脑血管病的影响宋艳引1,黄晓勇21•涿州市医院妇产科,河北涿州072750;2.涿州市医院神经内科，河北涿州072750［摘要］目的探讨阿托伐他汀强化治疗对缺血性脑血管病患者行妇科手术后近期脑血管意外事件的影响。方法整群选取2009年3月—2013年3月在涿州市医院患缺血性脑血管病患者行妇科手术治疗92例,按电脑随机数字法分为强化组46例和对照组46例（术前一周均停用阿司匹林肠溶片或硫酸氢氯毗格雷片及改善循环药物），强化组术前给予阿托伐他汀钙片t立普妥）80mg晚一次口服，
2、对照组给予阿托伐他汀钙片（立普妥）20mg晚一次口服，分别于术前、术后1周监测血糖、肝功能、肌酸激酶，观察术中、术后主要缺血性脑血管病事件。结果两组患者监测血糖、肝功能、肌酸激酶未见明显异常差别z强化组术中、术后1周未出现急性缺血性脑血管病，对照组出现2例脑梗塞、2例短暂性脑缺血发作，统计率为8%,P0.05,差异有统计学意义。结论缺血性脑血管病患者行妇科手术前给予阿托伐他汀强化治疗可有效降低术中及术后缺血性脑血管病脑卒中发生风险。关键词阿托伐他汀；缺血性脑血管病；妇科手术；缺血性脑血管病意夕卜［中图分类号］R45［文献标识码］A［文章编号］167
3、4-0742（2015）08（a）・0148-02EffectofdrugTreatmentonIschemicCerebrovascularDiseaseafterGynecologicalOperationSONGYan・yinl,HUANGXiao-yong21.DepartmentofObstetricsandGynecology,ZhuozhouHospital,Zhuozhou,HebeiProvince；072750China;2.DepartmentofNeurology,ZhuozhouHospital,Zhuozhou,Hebe
4、iProvince,072750China[Abstract]ObjectiveToobservetheinfluenceofatorvastatinintensivetreatmentoncerebralvascularaccidentsinpatientswithischemiccerebrovasculardiseaseaftergynecologicalsurgery.Methods92caseswereselectedwithischemiccerebrovasculardiseasesandunderwentgynecologicals
5、urgeryduringMarch2009toMarch2013,andwererandomlydividedintostrengtheninggroupandthecontrolgroupof46cases(preoperativeaweek,aspirinorclopidogrelsulfatetabletsandimprovingcirculationdrugsweredisabled).Beforesurgery,thestrengtheninggroupwastakenorallyeverynightaatorvastatin(Lipit
6、or)80mgzthecontrolgroupweretakenorallyeverynightaatorvastatinstatincalcium(Lipitor)20mgzThechangesofbloodglucose,liverfunction,creatinekinaseandmajorischemiccerebrovasculardiseaseweredetectedbeforeandafter1weeks.ResultsTwogroupsofpatientswithmonitoringofbloodglucose,liverfunct
7、ionandabnormalcreatinekinasenothadunobviousdifference.At1weekafteroperation,strengthenthegroupwithoutacuteischemiccerebrovasculardisease),thecontrolgrouphad2casesofcerebralinfarction,2casesoftransientischemicattack(TIA),thecountrateis8%,P0.05,thedifferencehasstatisticalsign讦ic
8、ance.ConclusionThetreatmentofischemiccerebrovasculardiseasewi
