材料科学与工程导论双语课件教学课件 作者 陈克正 王玮 刘春延 等编Chapter 9.ppt

《材料科学与工程导论双语课件教学课件 作者 陈克正 王玮 刘春延 等编Chapter 9.ppt》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、INTRODUCTIONTOMATERIALSSCIENCEANDENGINEERINGQingdaoUniversityofScience&TechnologyKezhengChenWeiWangChuntingLiu国家级双语教学示范课程ISSUESTOADDRESS...CHAPTER9BIOMATERIALS/NANOMATERIALS/SMARTMATERIALS•Whatarebiomaterials?•Whatisnano?•Whataresmartmaterials?•Applicationsofsm

2、artmaterialsAnInterdisciplinaryFieldBioengineersMaterialScientistsImmunologistsChemistsBiologistsSurgeons...9.1BiomaterialsALittleHistoryonBiomaterialsRomans,Chinese,andAztecsusedgoldindentistryover2000yearsago,Cunotgood.Ivory&woodteethAsepticsurgery1860(Lister

3、)Boneplates1900,joints1930Turnofthecentury,syntheticplasticscameintouseWWII,shardsofPMMAunintentionallygotlodgedintoeyesofaviatorsParachuteclothusedforvascularprosthesis1960-PolyethyleneandstainlesssteelbeingusedforhipimplantsWhat’sabiomaterial?1980-Passiveandi

4、nertpointofviewAnysubstanceordrugs,ofsyntheticornaturalorigin,whichcanbeusedforanyperiodaloneoraspartofasystemandthatincreasesorreplacesanytissue,organorfunctionofthebody.1990–ActivepointofviewNon-livingmaterialusedinamedicaldeviceanddesignedtointeractwithbiolo

5、gicalsystems.ClassificationofBiomaterialsFirstgeneration:INERTDonottriggeranyreactioninthehost:neitherrejectednorrecognition“donotbringanygoodresult”Secondgeneration:BIOACTIVEEnsureamorestableperformanceinalongtimeorfortheperiodyouwantThirdgeneration:BIODEGRADA

6、BLEItcanbechemicallydegradedordecomposedbynaturaleffectors(weather,soilbacteria,plants,animals)MeanFeaturesforMedicalApplicationsBIOFUNCTIONALITYPlayingaspecificfunctioninphysicalandmechanicaltermsBIOCOMPATIBILITYConceptthatreferstoasetofpropertiesthatamaterial

7、musthavetobeusedsafelyinabiologicalorganismTheabilityofamaterialtoperformwithanappropriatehostresponseinaspecificapplication.Hostresponse:thereactionofalivingsystemtothepresenceofamaterial.Whatisabiocompatiblematerial?1)Syntheticornaturalmaterialusedinintimatec

8、ontactwithlivingtissue(itcanbeimplanted,partiallyimplantedortotallyexternal).2)BiocompatiblematerialsareintendedtointerfacewithbiologicalsystemtoEVALUATE,TREAT,AUGMENTorREPL