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1、养血清脑颗粒治疗老年偏头痛性眩晕的效果doi:10.3969/j.issn.1007-614x.2014.22.50摘要目的:对比观察养血清脑颗粒对老年偏头痛性眩晕(MV)的治疗效果。方法:2011年10月-2013年3月收治MV患者78例,随机分为3组,养血清脑组给予养血清脑颗粒4g,3次/日。氟桂利嗪组给予氟桂利嗪5〜10mg,1次/晚。倍他司汀组给予倍他司汀4〜8mg/次,2〜4次/日。治疗12周,观察头痛、眩晕指标的变化及药物不良反应。结果:治疗后3组眩晕指标均显著改善。养血清脑颗粒对MV患者头痛指标的影响优于倍他司汀,对头痛时间、程度的影响优于氟桂利嗪,
2、对眩晕频率的影响与氟桂利嗪相当,对眩晕时间的影响与倍他司汀、氟桂利嗪相当,对眩晕强度的作用优于氟桂利嗪。治疗后,3组间眩晕残障量表(Dili)总评分差异无统计学意义(卩>0.05),养血清脑颗粒对DHT分项情绪评分的改善作用优于倍他司汀和氟桂利嗪。养血清脑组不良反应轻,耐受性良好。结论:养血清脑颗粒治疗老年MV安全、有效。关键词偏头痛性眩晕;养血清脑颗粒;氟桂利嗪;倍他司汀;预防治疗EffectofYangXueQingNaogranuleinthetreatmentofelderlymigrainevertigoZhouIluaxiangl,ChenChunfu
3、l,XuLiang2,WangWei3,WangGuoqing4,CaoYuling5,YanZhihui6DepartmentofNeurology,theProvincialHospitalAffiliatedtoShandong),2500211ShandongUniversity(JinanCity,DepartmentofNeurology,thePeople"sHospitalofZaozhuangArea,Shandong2771012DepartmentofNeurology,thePeople"sHospitalofLiaochengArea,S
4、handong2520003DepartmentofNeurology,thePeople,sHospitalofBinzhouArea,Shandong2566104DepartmentofNeurology,thePeople,sHospitalofJiningArea,Shandong2720005DepartmentofNeurology,YantaishanHospitalofYantaiCity,Shandong2640086Abstractobjective:Tocompareandobservethetreatment,effectofYangXu
5、eQingNaogranuleinelderlymigrainevertigo(MV)•Methods:78MVcaseswereselectedfromOctober2011toMarch2013.Theywererandomlydividedinto3groups.YangXueQingNaogroupweregivenYangXueQingNaogranule4g,3timesoneday.Flunarizinegroupweregivenflunarizine5〜10mg,1timeonenight.Betahistinegroupweregivenbet
6、ahistine4~8mgonetime,2~4timesoneday.After12weeksoftreatment,thechangsofheadache,vertigoindicatorsanddrugadversereactionwereobserved.Results:Aftertreatment,thevertigoindicatorof3groupsweresignificantlyimproved.TheeffectofYangXueQingNaogranuleontheheadacheindexofMVpatientswasbetterthanb
7、etahistine・Theeffectofthetimeanddegreeofheadachewasbetterthanflunarizine.Theeffectofthevertigofrequencywasequaltoflunarizine・Theeffectofthevertigotimewasequaltobetahistineandflunarizine.Theeffectofthevertigointensitywasbetterthanflunarizine・Aftertreatment,dizzinessdisabilityscale(DHI)
8、of3gr