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时间:2019-11-28
《冠状动脉钙化积分在冠心病诊断中的价值》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、江苏医药2015年4月第41卷第7期JiangsuMedJ,April2015,Vol41,No.7·773··论著·冠状动脉钙化积分在冠心病诊断中的价值陶俊利王跃涛王建峰邵晓梁陆培奇【摘要】目的探讨冠状动脉(冠脉)钙化积分(CACS)在冠心病(CAD)诊断中的价值。方法70例疑诊CAD患者均行CACS和冠脉造影(ICA)检查,用受试者工作特征(ROC)曲线评价CACS诊断CAD的效能,计算冠脉四大分支血管的CACS,分析分支血管CACS与相应分支血管狭窄的相关性。结果ICA金标准诊断CAD47例,非CAD23例。CAD组CACS高于非CAD组[(586.6±1
2、20.0)分vs.(69.7±67.1)分](P<0.01)。CAD组四大分支血管的CACS均高于非CAD组(P<0.01)。CACS诊断CAD的ROC曲线下面积为0.873,诊断CAD最佳界值为122分,灵敏度、特异度、准确度、阳性预测值和阴性预测值分别为70.2%、95.7%、78.6%、97.1%和38.9%。分支血管CACS与相应分支血管狭窄呈正相关(r=0.59,P<0.01)。结论CACS诊断CAD有一定价值,但不能全面评估冠脉狭窄程度。【关键词】冠状动脉钙化积分;冠心病【中图分类号】R445【文献标识码】A【文章编号】0253-3685(2015)
3、07-0773-03ValueofcoronaryarterycalciumscoreinthediagnosisofcoronaryarterydiseaseTAOJunli,WANGYuetao,WANGJianfeng,etal.DepartmentofNuclearMedicine,AffiliatedThirdHospital,SoochowUniversity,Changzhou213003,CHINA【Abstract】ObjectiveToevaluatethevalueofcoronaryarterycalciumscore(CACS)inth
4、ediagnosisofcoronaryarterydisease(CAD).MethodsSeventypatientswithsuspectedCADwereexaminedwithCACSandinvasivecoronaryangiography(ICA).CACSoffourmajorbranchvesselsofcoronaryarterywascalculated.TheperformanceofCACSinthediagnosisofCADwasevaluatedbydrawingreceiveroperationcurve(ROC).Theco
5、rrelationbetweenCACSofbranchvesselsandstenosisofcorrespondingvesselswasanalyzed.ResultsWithICAasgoldenstandard,CADwasdiagnosedin47cases(groupCAD)andnon-CADwasconfirmedin23cases(goupnon-CAD).CACSwashigheringroupCADthanthatingroupnon-CAD[(586.6±120.0)pointsvs.(69.7±67.1)points](P<0.01)
6、.SodidtheCACSoffourmajorbranchvesselsofcoronaryarteryingroupCAD(P<0.01).TheareaunderROCcurveforCACStodiagnoseCADwas0.873.Taking112pointsasthebestcutoffvalue,thesensitivitywas70.2%,specificitywas95.7%,accuracywas78.6%,positivepredictivevaluewas97.1%,andnegativepredictivevaluewas38.9%.
7、CACSofbranchvesselswaspositivelycorrelatedtothestenosisofcorrespondingvessels(r=0.59,P<0.01).ConclusionCACShasacertainvalueinthediagnosisofCAD,butcannotcomprehensivelyevaluatetheseverityofcoronarystenosis.【Keywords】Coronaryarterycalciumscore;Coronaryarterydisease[JiangsuMedJ,April201
8、5,41(7):773-
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