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1、临床动态循证抗感染治疗银屑病效果分析作者单位：474500河南省豫西协和医院；河南省西峡银屑病感染病因研究所通讯作者：袁鸿慈【摘要】目的探讨银屑病细菌性病因发病特点和动态循证抗感染治疗的效果。方法以细菌群相同步培养系统和复数菌直接药敏测试法，对住院病例的血和（或）尿进行培养和测试，选同一敏感抗感染药物，单品种、足剂量，由静脉缓慢给药，配合免疫双向调节剂辅助治疗，3个月为一个疗程。结果40例患者血培养计336例次，细菌L型生长，厌氧菌和需氧菌均未生长，培养次数最多23次，最少4次，平均10.1次；尿培养81例次，
2、需氧菌及兼性厌氧菌鉴定72株，细菌不稳定L型回复成细菌型鉴定27株。住院时间最长266d，最短45d,平均132.2do痊愈14例（35%）,基本痊愈17例（42.5%），好转9例（22.5%结论银屑病是以细菌稳定L型感染为主要特点的、内源性复数菌感染病，在机体天然免疫功能失调下，引发的全身性皮肤损害表象。在机体皮肤组织细胞准确休整配合下，动态循证选择敏感抗感染药物由静脉给药和免疫双向调节剂辅助治疗，可按期治愈。【关键词】银屑病；细菌群相同步培养系统；复数菌直接药敏试验；临床动态循证抗感染治疗；效果分析Dyn
3、amicevidence・basedclinicalanti-infectiontreatmenttoanalyzetheeffectofpsoriasisYUANHong-ci,LIUPei-feng,SUNFeng-run,LIXiao,LIXiao-wei,LITiao-huan,LIUFeng.InfectionintheEtiologyofPsoriasisSnstitute,WestHenanUnionHospital,Xixia474500,China[Abstract]ObjectiveToin
4、vestigatethecausesofpsoriasisandanti-bacterialtreatmentobservation.MethodsAdoptgroup-phasesynchronouscultureofbacteriaandfungipluraldirectsusceptibilitytestingmethod,culturebacterialandDrugsusceptibilitytestingthebloodandurineofhospitalizedpatients,choosethe
5、same,single,sensitive,adequatedoseantibioticsbyslowintravenousadiministration,withBi-directionalimmunemodulatortoAdjuvanttherap,3monthsforacourseoftreatment.Results40patientshaddonebloodculturewithatotalof336times,weicanobservategrowthofstsbleL-typebacterial
6、,thegrowthofanaerobicandaerobicbacteriawerenotfound;inwhichamaximumculturingof23times,atleast4times,withanaverageof10.1times.Bybacterialcultureofurine,weicanidentificateaerobicandfacultativeanaerobes72total;identificatebacteriaun-tableL-typewhichrevertingbac
7、ktobacteria27.Hospitalizedthelongest266days,theshortest45days,anaverageof132.2days・Cured14cases(35%),basicrecoveryin17patients(42.5%),improvementin9cases(22.5%).ConclusionPsoriasisisainfectiousdiseaseswhichisbasedoninfectionofstableL-typebacteriaandendogenou
8、sinfectioncomplexbacterialoUnderthenaturalimmunedysfunctionofbody,causedsystemicdamagetotheappearanceofskin,Withtherestaccuratingofskintissueinthebody,slectesensitiveantibiotics,bytheintravenous
