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1、银杏达莫注射液治疗糖尿病肾病的疗效观察［摘耍］冃的：探讨和分析银杏达莫注射液治疗糖尿病肾病的临床效果及应用价值。方法：冋顾性分析80例糖尿病肾病患者，按照入院时间先示将其分为对照纟fl和观察组，每组各40例。观察组在采用常规降血糖、控高血压的治疗基础上加用银杏达莫注射液20ml加入250ml生理盐水中，每日1次缓慢静滴。对照组仅采用常规降血糖、控高血压、血脂等治疗。两组疗程均为2周。观察和分析两组治疗前后血尿素氮(BUN)及血清肌酹(Scr)的变化情况，比较两组临床治疗效果。结果：治疗2周后，观察纽治疗总有效率为100.0%,对照组治疗总有效率为85.0%,两组总有效率比较差异有统计
2、学意义(x2=4.5,P<0.05)；观察组BUN、Scr与治疗前相比,明显降低(t=2.69、2.32,均P<0・05)；对照组BUN与治疗前相比明显降低(t=2.07,P<0.05),Scr改善差异无统计学意义("0.78,P>0.05)；观察组治疗后BUN、Scr与对照组相比，均明显下降，差异冇统计学意义(t=2.13、2.07,均P<0.05)o结论：银杏达莫注射液治疗糖床病肾病患者临床效果确切，能够延缓肾功能恶化，通过扩血管、抗血栓、抗自由基损伤、改善微循环，提高患者的牛存质量，对糖尿病肾病具有保护和治疗作用。［关键词］银杏达莫注射液；糖尿病肾病；血尿素氮；血清肌酹［中图分
3、类号］R587.5［文献标识码］B［文章编号J1673-7210(2011)08(a)-156-02ObservationontherapeuticeffectsofGinkgodipyidamo1umInjectioninthetrcatmentofdiabeticnephropathyYUANShengyong,ZOUGuoxinDepartmentofPharmacy,thePeople‘sHospitalofMaomingCity,GuangdongProvince,Maoming525000,China［Abstract］Objective:Toinvestigateand
4、analyzetheclinicaleffectsandvalueofGinkgodipyidamolumInjcctioninthetreatmentofdiabeticnephropathy・Methods:Aretrospectiveanalysisof80patientswithdiabeticnephropathy,whoweredividedintocontrolgroupandobservationgroupwith40patientsforeach.Theobservationgroupwasgivenslowintravenousinfusionof20mlofGi
5、nkgodipyidamolumInjectiondissolvedin250mlofNormalSalineonceadayonthebasisofconventionalhypoglycemictreatmontandhypertensioncontroltreatment.Thecontrolgroupwason1ygivenconventionalhypoglycemictreatment,hypertensioncontroltreatment,hyperlipidemiacontroltreatmentandothers.Thecoursesoftreatmentforb
6、othgroupswere2weeks.Throughobservingandanalyzingthebloodureanitrogen(BUN)andserumcrcatinine(Scr)changesbeforeandaftertreatment,thetherapeuticeffectsoftwogroupswerecompared・Results:Theclinicaleffectsoftwogroupswerecomparedafter2weeks.Thetotaleffectiverateoftheobservationgroupwas100.0%whilethatof
7、thecontrolgroupwas85.0%,withsignificantdifference(x2=4.5,P<0.05).TheBUNandScroftheobservationgroupaftertreatmentdecreasedsignificantlycomparedwiththosebeforetreatment(t=2.69,2.32,allP<0.05).TheBUNofthecontrolgroupaftertreatmentdec
