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1、甲状腺相关眼病的临床分析【摘要】廿的：分析1T1状腺相关眼病(thyroidassociatedophthalmopathy,TAO)的临床特点，为诊断和治疗提供依据。方法：冋顾性分析我院自200107/200710就诊的268例473眼TAO患者的临床资料。结果:在268例就诊的TAO患者中，甲状腺功能异常者213例(79.5%),眼睑退缩299眼(63.2%),迟落261眼(55.2%),眼睑肿胀277眼(58.6%),球结膜充血、水肿164眼(36.7%),角膜点状上皮脱落39眼(8.3%),角膜溃疡8例(1.7%),眼球突出422例(89.2%),眼压升高
2、者43例(16.0%)69眼(14.6%)，眼球运动受限332眼(70.2%),其中单方血眼球运动受限者143眼(43.1%),单方血眼球运动受限顺序依次是下转，内转，上转,外转，多方面眼球运动受限者176眼(53.0%),眼球固定13眼(3.9%),M71例(26.5%),影像学肌肉测量，眼外肌受累频率由高到低依次是卜卫肌、上立肌、内立肌、外立肌，视神经病变者31例(11.6%)57眼。结论：TAO的发病多与甲腺功能有关，临床表现有自身特点，人多数患者易于诊断，对于不典型病例要注意眼征特点，眼外肌受累情况以及影像学意义。【关键词】甲状腺相关眼病眼球突出眼内压眼外
3、肌视神经ClinicalanalysisofthyroidassociatedophthalmopathyDaWenZheng,HongWang,YanLuoShanxiEyeHospital,Taiyuan030002,ShanxiProvince,ChinaAbstractAIM:Toanalyzetheclinicalcharacteristicofthyroidassociatedophthalmopathy(TAO)soastoprovidebasesforthediagnosisandtreatment.METHODS:Theclinicaldatao
4、f268patients(473eyes)withTAOfromJuly2001toOctober2007inourhospitalwasanalyzedretrospectively.RESULTS:Therewere213eyes(79.5%)ofgkindulathyreoideadisfunction,299eyes(63.2%)oflidretraction,261eyes(55.2%)ofdelayshed,277eyes(5&6%)ofeyelidengorgement,164eyes(36.7%)ofconjunctivalcongestion,d
5、ropsy,39eyes(8.3%)ofkeratodermapunctiformEPIdefluvium,8eyes(1.7%)ofcornealulcer,422eyes(89.2%)ofexophthalmos,69eyes(14.6%)ofintraoculartensionstepupin43patients(16.0%),332eyes(70.2%)ofocularlimitationofmovement.Amongthetotal,onesidedocularlimitationofmovementeyeswere143(43.1%),theorde
6、rofonesidedocularlimitationofmovementwasdeorsumduction,adversion,superductionandexodeviatiortVersatilityocularlimitationofmovementeyeswere176(53.0%),eyeglobefixing13(3.9%),ambiopia71(26.5%);Accordingtomusclemeasureofimageology,thefrequencyofEOMtobeinvolvedfromhightolowwasinferiorrectu
7、s,superiorrectusmuscle,internalrectusmuscle,externalrectusmuscle.Theopticneuropathypatientswere31(11.6%),totally57eyes.CONCLUSION:ThemorbidityofTAOisrelatedtoabnormalthyroidfunction,andtheclinicalmanifestationhasitsowncharacteristics,sothemostcasesareeasytodiagnose.Itisimportanttopaya
8、ttent
