资源描述:
《普萘洛尔、速尿治疗晚期肝癌及肝转移癌合并腹水观察》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、普蔡洛尔、速尿治疗晚期肝癌及肝转移癌合并腹水观察;作者:李莹,黎苗,翟艳辉,关展鸿毕业论文【关键词】;晚期肝癌;肝转移癌;腹水;普蔡洛尔;速尿毕业论文[摘要];目的;晚期肝癌及肝转移癌多并发腹水,治疗较困难。笔者在抗癌,纠正水、电解质紊乱及低蛋白血症的基础上,观察普蔡洛尔、速尿治疗的效果。方法;54例病人常规检查,排除心脏疾病后,给予口服普蔡洛尔10mg,3次/d;速尿20mg,3次/d。每天测量腹围、记录尿量,定期检查水、电解质,适量补充钾,纠正低蛋白血症。连用1周,有效后继续使用至1个月,无效者停用。结果;54例病人中好转12例,有效26例,显效
2、8例,无效8例,总有效率85.2%O结论;普蔡洛尔、速尿联合治疗晚期肝癌及肝转移癌并发腹水,可降低门静脉高压,减轻腹水,且无特殊副作用,值得继续研究。毕业论文[关键词];晚期肝癌;肝转移癌;腹水;普蔡洛尔;速尿毕业论文Propranoloandfurosemideintreatmentofadvancedhepatocarcinomaandmetastaticcarcinomawithascites毕业论文[Abstract];Objective;lt5sdifficulttotreattheascitesinhepatocarcinomaorliv
3、ermetastaticcarcinomapatients.Weobservedthecircumstanceofascitesof54hepatocarcinomaorlivermetastaticcarcinomapatients,whoreceivedpropranololandfurosemidebesidesanticancertherapy,rectifyingtheabnormalelectrolyteandhypoproteinemia,andobtainedthegoodeffect.Methods;54patientswithou
4、tcardiovasculardiseasesweregivenpropranololatthedoseof10mgeverytime,3timesperdayandfurosemideatthedoseof20mgeverytime,3timesperdayforaweek.Measuringabdominalperimeterandrecordingtheurinevolumeeveryday,checkingelectrolytebalaneeperiodically,andcomingitback,andrectifyinghypoprote
5、inemia.Theprescriptionwasadministeredsequentiallyifeffective,orstopped.Results;54patientswereevaluableforresponse.Theoverallresponseratewas85.2%(12patientswereimprovement,26wereeffectiveand8werevalid).8patientswerenoresponse.Conclusion;Propranololwithfurosemidecombinationiseffe
6、ctivetodepresshighpressureofportalisanderupttheascites.andwelltoleratedinhepatocarcinomaorlivermetastaticcarcinomapatients.Soitisworthytobefurtherstudied・毕业论文[Keywords];advancedhepatocarcinoma;livermetastaticcarcinomajascites;propranolol;furosemide毕业论文晚期肝癌及肝转移癌多合并腹水,治疗十分棘手,病人也很
7、痛苦,生活质量低下。近几年来我们试用普蔡洛尔加速尿治疗晚期肝癌及肝转移癌合并腹水病人54例,减轻了症状,改善了患者的生活质量,取得了较好的效果,现总结如下。毕业论文1;资料与方法毕业论文1.1;一般资料;54例病人全部经MR、CT、影像学以及病理学确诊为肝癌或肝转移癌,其中男33例,女21例,年龄28-67岁,中位年龄50.5岁,腹围96-118cm,平均108cm0KPS评分均在30分以上。毕业论文1.2;治疗方法;(1)常规心电图检查,除外心率失常和传导阻滞;血电解质、肝功能检查。(2)常规测量腹围,并记录。(3)如无心脏疾病及电解质紊乱者,给予
8、心得安10mg,速尿20mg,3次/d,连用7天,每天测量腹围,并记录24h尿量。如尿量增多,腹围减少则继续