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1、早期振幅整合脑电图(aEEG)监测对新生儿脑损伤早期诊断的意义【摘耍】目的：探讨早期振幅整合脑电图QEEG)监测在新生儿脑损伤早期诊断中的应用价值。方法：选择2014年6-12月本院出生及外院转入的60例脑损伤高危因索的新生儿为观察组，另选取同期本院出生30例无脑损伤的新生儿作为对照组。比较aEEG的背景活动、连续性评估、睡眠-觉醒周期以及惊厥存在情况在两组新牛儿间是否存在差异。结果：观察组中aEEG背景活动正常者12例(20.0%),轻度异常者22例(36.7%),重度异常26例(43.3%),与对照组比较差异有统计学意义(P〈0.
2、05)。观察组中aEEG连续性11例(27.5%),不连续性27例(45.0%),持续性低电压23例(36.7%),与对照组比较差异有统计学意义(P<0.05)o观察组屮&EEG连续性无睡眠-觉醒周期者19例(31.7%),不成熟睡眠-觉醒周期者28例(46.7%),成熟睡眠-觉醒周期者13例(21.7%),与对照组比较差异有统计学意义(P〈0・05)。观察组中单个惊厥者9例(15.0%),反复惊厥者34例(56.7%),癫痫持续状态者17例(28.3%),与对照组比较差异有统计学意义(P〈0・05)。结论：脑损伤高危新生儿的振幅整合
3、脑电图(aEEG)临测结果与正常新生儿间存在显著性差异，临床可采用aEEG作为早期脑损伤诊断的检查方式。【关键词】振幅整合脑电图；新生儿；脑损伤；早期诊断【Abstract】Objective：TostudytheapplicationvalueofearlydetectionofaEEGontheearlydiagnosisofcerebralinjuryfornewborns・Method：60patientswithcerebralinjuryinourhospitalandtransferredfromotherhospita
4、lswereselectedfromJune2014toDecember2014astheobservationgroup,whi1e30healthynewbornsinourhospitalwereselectedasthecontrolgroup.TheaEEGbackgroundactivity,continuousassessment,sleep-awakencycleandconvulsionsoftwogroupswerecompared.Result：TheaEEGbackgroundactivityofobserva
5、tiongroupwere12cases(20.0%)normal,22cases(36.7%)minimalabnormaland26seriouscases(43.3%),comparedwiththecontrolgroupofthatthedifferenceswerestatisticallysignificant(P<0.05).TheaEEGcontinuityofobservationgroupwere11(27.5%)casescontinuous,27cases(45.0%)discontinuousand23ca
6、ses(36.7%)withcontinuouslowcephalogram,comparedwiththecontrolgroupofthatthedifferenceswerestatisticallysignificant(P<0.05).Forobservationgroup,therewere19cases(31.7%)withsleepless-awakencycle,28cases(46.7%)withimmaturesleep-awakencycleand13cases(21.7%)withmaturesleep-aw
7、akencycle,comparedwiththecontrolgroupofthatthedifferenceswerestatisticallysignificant(P〈0・05).Forobservationgroup,therewere9cases(15・0%)withconvulsion,34cases(56.7%)withrepeatedconvulsionsand17cases(28.3%)withcontinuousepilepsy,comparedwiththecontrolgroupofthatthediffer
8、enceswerestatisticallysignificant（P〈0.05）・Conclusion：TheaEEGtestresultsfornewbornswithcerebralinjuryissignific
