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1、角膜塑形镜治疗近视的临床观察和并发症分析作者：王跃静，陈独娅，成伟，张传伟【摘要】冃的：观察角膜塑形镜治疗近视的临床效果和并发症，并分析其相关因素。方法：选择由三个眼科屮心提供的配戴角膜塑形镜的病历资料，患者共302例601眼，观察戴镜后lwk;l,3mo的裸眼视力、屈光状态、0RBSCAN检查、角膜荧光素染色裂隙灯显微镜检查的情况。所有观察病例的治疗前设为自身对照组。结果：戴镜后lwk;l,3mo的裸眼视力分别与戴镜前裸眼视力比，均有统计学意义(t二95.920,77.710,65.362;P<0.01,&11;0.01,<0.01);戴镜后lwk
2、：1,3mo的裸眼视力与戴镜前矫正视力lwk;1,3mo比，均无统计学意义(t二1.364,0.599,0.581;P=0.174,0.550,0.562);戴镜后lwk;l,3mo的角膜前表面水平向曲率与戴镜前角膜前表面水平向曲率比，均有显著统计学意义(t二26.020,20.143,17.476：P<0.01,<0.01,<0.01);戴镜后lwk;l,3,6mo的角膜前表面垂直向曲率与戴镜前角膜前表面垂直向曲率比，均有显著统计学意义(t=22.505,20.626,21.667,25.397;P<0.01,<0.01,<
3、0.01,<0.01);发生角膜上皮点状脱落和角膜中央明显压痕的病例在lwk时占7.5%,Imo时占6%,3mo占9.8%,其中反复出现角膜上皮点染和明显压痕的占2.5%o结论：角膜塑形镜治疗近视具有特有的降低近视度数速度快、效果显著、安全、可逆的优势，但矫正近视度有一定适用范围。【关键词】角膜塑形镜;治疗;近视AbstractATM:Toobservetheclinicaleffectsandcomplicationsoforthokeratologylensformyopia,andtoanalyzetherelevantfactors.METHODS
4、:Themedicalrecordsoforthokeratologylenswearer302cases601eyesfromthreeeyecenterswereanalyedandtheuncorrectedvisualacuity,refraclivestalus,Orbscanexamination,fluoresceinstaininglweek;lmonth,3monthsafterwearingglasseswereobserved・Theconditionofallpatientsbeforetreatmentwasregardedascont
5、rolgroup.RESULTS:Therewassignificantdifference1week:lmonth,3monthsafterwearingglassescomparedwithbeforewearingglassesinuncorrectedvisualacuity(t=95.920,77.710,65.362;P<0.01,<0.01,<0.01),theanteriorcornealsurfacehorizontalcurvature(t=26.020,20.143,17.476;P<0.01,<0.01,&I
6、t;0.01)andtherewassignificantdifferencelweek,lmonth,3,6monthsafterwearingglassescomparedwithbeforewearingglassesintheanteriorcornealsurfaceperpendicularcurvature(t二22.505,20.626,21.667,25.397;P<0.01,<0.01,<0.01,<0.01);IIowever,Therewerenosignificantdifferenceinuncorrected
7、visualacuitylweek;lmonth,3monthsafterwearingglassescomparedwiththecorrectedvisualacuitybeforewearingglasses・(t二1.364,0.599,0.581:P=0.174,0.550,0.562);Thepunctatelossofcornealepitheliumandindentationofcentercorneaappearediniweekwas7.5%,lmonth6%,3months9.8%,ofwhichrecurrenceratiowas2.5
8、%.CONCLUSION
